Succinic Actinobacillus succinogenes

Succinic Acid Production from Cheese Whey using Actinobacillus succinogenes 130 Z... 

Three important natural succinate producers, Actinobacillus succinogenes, Mannheimia succiniciproducens, and Basfia succiniciproducens, all members of the Pasteurellaceae family within the y-proteobacteria, were isolated from mmen contents (Guettler et al., 1999 Lee et al., 2002 Kuhnert et al., 2010). All three species are capnophilic (thrive in the presence of high concentrations of carbon dioxide), facultative anaerobic bacteria which share a similar fermentative metabolism resulting in the production of succinate as major product accompanied by pyruvate dissimilation to lactate, acetate, formate, and in some cases to ethanol as minor products. 

Borges ER, Pereira N Jr. (2011). Succinic acid production from sugarcane bagasse hemi-ceUulose hydrolysate by Actinobacillus succinogenes. J Ind Microbiol Biotechnol, 38, 1001-1011. 

Chen K, Jiang M, WeiP, Yao J, Wu H. (2010). Succinic acid production from acid hydrolysate of corn fiber by Actinobacillus succinogenes. Appl Biochem Biotechnol, 160, 477-4 85. 

Chen KQ, Li J, Ma JF, Jiang M, Wei P, Liu ZM, Ying HJ. (2011). Succinic acid production by Actinobacillus succinogenes using hydrolysates of spent yeast cells and corn fiber. Bioresource Technol, 102,1704—1708. 

Guettler MV, Rumler D, Jain MK. (1999). Actinobacillus succinogenes sp. nov., a novel succinic-acid-producing strain from the bovine rumen. Int J Syst Bacteriol, 49, 207-216. 

Kim P, Laivenieks M, Vieille C, Zeikus JG. (2004c). Effect of overexpression of Actinobacillus succinogenes phosphoenolpyruvate carboxykinase on succinate production in Escherichia coli. Appl Environ Microbiol, 70, 1238-1241. 

Liu YP, Zheng P, Sun ZH, Ni Y, Dong JJ, Zhu LL. (2008). Economical succinic acid production from cane molasses hy Actinobacillus succinogenes. Bioresource Technol, 99,1736-1742. 

McKinlay JB, Laivenieks M, Schindler BD, McKinlay AA, Siddaramappa S, Challacombe JF, Lowry SR, Clum A, Lapidus AL, Burkhart KB, Harkins V, Vieille C. (2010). A genomic perspective on the potential of Actinobacillus succinogenes for industrial succinate production. BMC Genomics, 11, 680. 

Wan C, Li Y, Shahbazi A, Xiu S. (2008). Succinic acid production from cheese whey using Actinobacillus succinogenes 3(fL. Appl Biochem Biotechnol, 145, 111-119. 

Ye GZ, Jiang M, Li J, Chen KQ, Xi YL, Liu SW, Wei P, Ouyang PK. (2010). Isolation of NH4+-tolerant mutants of Actinobacillus succinogenes for succinic acid production by continuous selection. J Microbiol Biotechnol, 20, 1219-1925. 

Yu J, Li Z, Ye Q, Yang Y, Chen S. (2010). Development of succinic acid production from corncob hydrolysate hy Actinobacillus succinogenes. J IndMicrobiol Biotechnol, 37,1033-1040. 

Zheng P, Dong JJ, SunZH, Ni Y, FangL. (2009). Fermentative production of succinic acid from straw hydrolysate hy Actinobacillus succinogenes. Bioresource Technol, 100, 2425-2429. 

Corn stover Diluted alkaline 10.5% WIS Actinobacillus succinogenes No Succinic acid SSE Batch... 

Urbance, S.E., Pometto, A.L. Ill, DiSpirito, A.A., and Denli, Y. (2004) Evaluation of succinic acid continuous and repeat-batch biofilm fermentation by Actinobacillus succinogenes using plastic composite support bioreactors. Appl. Microbiol Biotechnol, 65, 664-670. 

Chen KQ, Zhang H, Miao YL, Jiang M, Chen JY (2010) Succinic acid production Irom enzymatic hydrolysate of sake lees using Actinobacillus succinogenes 130Z. Enzyme Microb Technol 47 236-240... 

Kim DY, Yim SC, Lee PC, Lee WG, Lee SY, Chang HN (2004b) Batch and continuous fermentation of succinic acid from wood hydrolysate by Mannheimia succiniciproducens MBEL55E. Enzyme Microb Technol 35 648-653 Kim P, Laivenieks M, Vieille C, Zeikus JG (2004c) Effect of overexpressirai of Actinobacillus succinogenes phosphoenolpyruvate carboxykinase on succinate productirai in Escherichia coli. Appl Environ Microbiol 70 1238-1241... 

Lin CSK, Du CY, Koutinas A, Wang R, Webb C (2008) Substrate and product inhibition kinetics in succinic acid production hy Actinobacillus succinogenes. Biochem Eng J 41 128-135 Lin H, Bennett GN, San KY (2005) Fed-batch culture of a metabolically engineered Escherichia coli strain designed for high-level succinate production and yield under aerobic conditions. Biotechnol Bioeng 90 775-779... 

Zheng P, Fang L, Xu Y, Dong JJ, Ni Y, Sun ZH (2010) Succinic acid production from com stover by simultaneous saccharification and fermentation using Actinobacillus succinogenes. Bioresour Technol 101 7889-7894... 

Amerobiospirullum succiniciproducens, and Actinobacillus succinogenes as well as genetically engineered strains of E. coli and Corynebacterium glutamicum. Also, newly discovered species of bacteria Basfia succiniciproducens have been reported by Scholten and Dagele (2008) to have exceptional promise for the fermentation of glycerol to succinic acid. 

Lin, S.K.C., Du, G., Koutinas, A., Wang, R., Webb, G., 2008. Substrate and product inhibition kinetics in succinic acid production by Actinobacillus succinogenes. Biochemical Engineering Journal 41 (2), 128-135. 

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