Succession uncontrollable

The use of computer algorithms to deconvolute MALDI or ESI spectra of mixtures of microorganisms obtained under uncontrolled conditions is less likely to be successful, as discussed above. 

Damaging fires are uncontrolled chemical reactions, so fire hazards involving ordinary flammable and combustible materials could be included in the above definition of chemical reactivity hazards. However, this publication seeks to supplement basic fire prevention and protection measures by addressing how to successfully manage other chemical reactivity hazards in the work environment. Consequently, the use of the term "chemical reactivity hazards" in this publication will not include explosion, fire and dust explosibility hazards involving the burning of flammable and combustible materials in air. Storage and use of commercial explosives is also outside the scope of this publication. 

In order to develop a process that is more robust and free from some of the limitations of the double-antibody concept, various methods have been explored to immobilize the primary antibody onto the solid phase. Covalent immobilization of the immunoreactive species directly on a solid support would have the distinct advantage of overcoming the capacity limitations and the possible molecular changes that can take place before or after immobilization. However, this mode has not been widely utilized due to lack of successful and reproducible methods of covalent attachment. A further complication is the uncontrollable heterogeneity of the solid supports used currently for immobilization. Realizing these limitations, the approach used for Stratus has been to choose a design... 

Dicamba (3,6-dichloro-2-methoxybenzoic acid) is primarily used as a postemergence broadleaf herbicide, which interferes with normal plant auxin function, subsequently causing uncontrolled growth and the inhibition of the phototropic and geotropic function. Cumulative response results in plant death. The success of auxinic analogues such as Dicamba and 2,4-dichloropheno-xyacetic acid in weed control has led to widespread manufacturing and use. Estimated U.S. production for Dicamba was 5 million kg in 1990 [391]. 

Valproate, a simple branched-chain fatty acid, was first reported as a successful treatment for acute mania by Lambert and colleagues in 1966. Following this report, at least 16 uncontrolled trials consistently supported the observation that valproate has acute and long-term mood-stabilizing effects in patients with bipolar disorder (reviewed by Keck et al. 1992a). Recently, five double-blind controlled studies of valproate have been completed that provide definitive evidence of its efficacy in acute mania. 

We suspect that the assumed physiological mechanism of pain and heart responses may have facilitated self-deception in the first experiment. Most people believe that such responses are not under an individual s voluntary control. This widespread belief makes it very easy to deny to oneself that the action was deliberately enacted to make a cheerful diagnosis, for how does one intentionally pull the strings. That self-deception may occur more often and be more successful for actions (incorrectly) believed to be uncontrollable than controllable is an interesting question for further research. The possibility of a motivational placebo effect, in which the desire to have one s tolerance shifted produces actual changes in physiological tolerance thresholds, seems worth exploring. 

It should be appreciated at the outset that the problem of optimum determination can be quite complicated. In many cases a wide range of choice is possible for the controllable variables. As more and more variables are taken into consideration, the problem becomes more difficult at an increasing rate. Furthermore, in many cases the optimization problem is continually recurring that is, a study may be successfully concluded and an optimum set of values for the controllable variables determined, but at a later time, owing to changes in uncontrollable variables (supply and quality of raw materials, demand and specifications for products, tax laws, etc.), the calculated optimum is no longer valid and must be determined again. 

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