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Hematological Effects. Leukocytosis and decreased platelet counts were reported in a group of subjects shortly after they ingested an unknown amount of endosulfan (Blanco-Coronado et al. 1992). One subject from that study, who eventually died, had prolonged partial thromboplastin time and prothrombin time with thrombocytopenia, and decreased fibrinogen two days after being admitted to the hospital. Elevated white cell count was also observed in an additional case of fatal acute poisoning with... 

The solubility of salts is an important criterion in sample preparation, as is the ionic character of drugs and larger molecules. One of the techniques used to increase the solulxlity of a dn is to convert the drtg from an insoluble form to a soluble salt (more on thfe subject shortly). Common drug salts include sodium, caldum, sulfates, chlorides, tartratesy citrates, and lactates. The pH also plays a critical role in the water solubility of drvgs and will be examined in detail momentarily. Soluble compounds are characterized as hydrophilic or lipophobic, for reasons to be discussed next. 

As you get started going through the chapters of the text, try to anticipate upcoming subjects in your lecture sessions. Read chapter material on those subjects shortly before the lecture. In other words, read ahead. a first reading, it is not necessary to strive for 100% comprehension, and you may choose to ignore a lot of the mathematical detail. Simply try to get the direction of the presentation and a general feel for the subtopics. Then, follow your instructor s lecture closely, especially to see the areas that your instructor has selected to emphasize. 

The sample is again subjected to a constant magnetic field but all the nuclei are excited by a very short radio frequency pulse. The frequency e (e.g., 400 MHz for a proton at 9.4 tesla) is applied over a period of several... 

Generally speaking, intermolecular forces act over a short range. Were this not the case, the specific energy of a portion of matter would depend on its size quantities such as molar enthalpies of formation would be extensive variables On the other hand, the cumulative effects of these forces between macroscopic bodies extend over a rather long range and the discussion of such situations constitutes the chief subject of this chapter. 

This venerable book was written in 1935, shortly after the birth of modern quantum mechanics. Nevertheless, it remains one of the best sources for students seeking to gain an understanding of quantum-mechanical principles that are relevant in chemistry and chemical physics. Equally outstanding jobs are done in dealing with both quantitative and qualitative aspects of the subject. More accessible to most chemists than Landau and Lifschitz. 

Scott S K 1994 Oscillations, Waves and Chaos in Chemical Kinetics (Oxford Oxford University Press) A short, final-year undergraduate level introduction to the subject. 

Simulation runs are typically short (t 10 - 10 MD or MC steps, correspondmg to perhaps a few nanoseconds of real time) compared with the time allowed in laboratory experiments. This means that we need to test whether or not a simulation has reached equilibrium before we can trust the averages calculated in it. Moreover, there is a clear need to subject the simulation averages to a statistical analysis, to make a realistic estimate of the errors. 

An alternative approach to obtaining microwave spectroscopy is Fourier transfonn microwave (FTMW) spectroscopy in a molecular beam [10], This may be considered as the microwave analogue of Fourier transfonn NMR spectroscopy. The molecular beam passes into a Fabry-Perot cavity, where it is subjected to a short microwave pulse (of a few milliseconds duration). This creates a macroscopic polarization of the molecules. After the microwave pulse, the time-domain signal due to coherent emission by the polarized molecules is detected and Fourier transfonned to obtain the microwave spectmm. 

A laser beam is capable of putting so much energy into a substance in a very short space of time that the substance rapidly expands and volatilizes. The resulting explosive shock wave travels through the sample, subjecting it to high temperatures and pressures for short times. This process is also known as ablation. 

Antiwear premium hydrauHc fluids represent the largest volume of hydrauHc fluids used. Shortly after their introduction in 1960, a second product group was formulated, characterized by the same antiwear characteristics but having lower pour points and higher viscosity indexes. These were formulated for use in mobile and marine appHcations subject to temperature extremes. 

There are several methods to determine and compare the resistance to partial discharges. Some tests are done on finished cables, such as the U-bend test, and others are done on laboratory samples molded from the insulation, that are subjected to partial discharges created by sharp objects, such as needles under high voltages. The tests compare either the energy required or the length of time required to erode or fail (short circuit) samples of similar thickness. 

Ra.m Tensile. A ram tensile test has been developed to evaluate the bond-2one tensile strength of explosion-bonded composites. The specimen is designed to subject the bonded interface to a pure tensile load. The cross-section area of the specimen is the area of the aimulus between the outer and inner diameters of the specimen. The specimen typically has a very short tensile gauge length and is constmcted so as to cause failure at the bonded interface. The ultimate tensile strength and relative ductihty of the explosion-bonded interface can be obtained by this technique. 

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