Stroke diabetes and

At one time polyphenolics were regarded as antinutrients since they can complex with proteins and reduce protein quality. Today s heightened interest in these compounds is due to possible health benefits that are attributed to their antioxidant properties. The possible health benefits include reduced risk of coronary heart disease, cancer, stroke, and diabetes. In addition to these health-related findings, it has been long recognized that... 

Anthocyanins are a class of flavonoids separated from proanthocyani-dins. Anthocyanins have been known to be highly protective and therapeutic against especially age-related diseases such as hypertension, cardiac infraction and cerebral infarction. Additionally, because the colors of anthocyanins could help to ease psychic and physical troubles or tiredness, the anthocyanins could not only relax us, but also the colors themselves could prevent and remedy many diseases, especially, age-related diseases such as hypertension, heart failure, stroke and diabetes. Generally, anthocyanins have antioxidant properties, which could protect and enhance our body systems with bioactive abilities such as the immuno-, anticancer-, antimicrobial potencies and others. 

Micha R, Mozaffarian D. Saturated fat and cardiometabolic risk factors, coronary heart disease, stroke, and diabetes afresh look at the evidence. Lipids. 2010, 45 893-905. 

Woo J, Lam CW, Kay R, Wong AH, Teoh R, Nicholls MG. The influence of hyperglycemia and diabetes melhtus on immediate and 3-month morbidity and mortality after acute stroke. Arch Neurol 1990 47 1174-1177. 

Demchuk AM, Morgenstem LB, Krieger DW, Linda Chi T, Hu W, Wein TH, Hardy RJ, Grotta JC, Buchan AM. Serum glucose level and diabetes predict tissue plasminogen activator-related intracerebral hemorrhage in acute ischemic stroke. Stroke 1999 30(l) 34-39. 

Hypertension is strongly associated with type 2 diabetes.6 The added comorbidity of hypertension in diabetes leads to a higher risk of cardiovascular disease (CVD), stroke, renal disease, and diabetic retinopathy leading to greater health care costs.7... 

Father had stroke at age 59 mother has history of hypertension and diabetes mellitus... 

We still need much better medicines to cure cancer, heart disease, stroke, and Alzheimer s disease. We need better drugs to deal with obesity, diabetes, arthritis, and schizophrenia. The treatments of diabetes, arthritis, and mental defects such as schizophrenia or manic depression are not yet cures, just ways to keep the symptoms under control. Cures are needed. Insights from genetics may help guide us toward elegant and rational cures, but we will also make use of screens to identify natural products and libraries of randomly generated synthetic compounds (combinatorial chemistry). A semi-empirical approach may be the best hope over the next two decades to yield drugs to alleviate these diseases. 

Diabetes is a global epidemic affecting more than 240 million people worldwide. The incidence of this disease is growing at an alarming rate, with 380 million cases predicted by 2025. Each year over 3.8 million people die from complications of diabetes, including heart disease, stroke and kidney failure. The vast majority... 

A family medical history can identify people with a higher-than-usual chance of having common disorders, such as heart disease, high blood pressure, stroke, certain cancers, and diabetes. These complex disorders are influenced by a combination of genetic factors, environmental conditions, and lifestyle choices. A family history also can provide information about the risk of rarer conditions caused by mutations in a single gene, such as cystic fibrosis and sickle cell anemia. 

The potential contribution of stem cells to medical treatment lies in then-capability to differentiate and grow into normal, healthy cells. Using pluripotent stem cells, scientists are devising means to culture them in the laboratories and coax them to grow into various specialized cells. Rather than gene therapy, with stem cells we have the potential of cell therapy to repair our diseased tissues and organs. This will circumvent the lack of donor organs. Stem cells also provide the possibility for healthy cells to cure disabilities such as strokes, Parkinson s disease, and diabetes. 

As noted above, obesity is a health problem. It is associated with both elevated mortality and morbidity. More specifically, obesity is a risk factor for cardiovascular disease, including heart attack and stroke, and for high blood pressure (hypertension), diabetes, and hyperlipidemia (elevated levels of lipids in the blood, a risk factor for atherosclerosis and its sequelae), and for cancer. 

The risk factors for vascular dementia are essentially the same as those for stroke and heart attack. They include high blood pressure, heart disease, diabetes mellitus, sickle cell disease, obesity, smoking, alcohol use, depression, and high cholesterol levels. 

In many parts of Britain in the 1930s, excellent records of the hirthweight of hahies were made. When the causes of death in the subsequent adults were studied and medical records investigated, a strong correlation between low hirthweight, stroke incidence of mortahty from cardiovascular disease and diabetes was observed (Barker, 1998). It may be that low hirthweight is due to undemutrition of the mother. 

As the prevalence of obesity increases worldwide, so does the prevalence of associated co-morbidities type-2 diabetes, chronic obstructive sleep apnoea, cardiovascular disease (hyper-tension, coronary artery disease and congestive heart failure, stroke and peripheral vascular disease), fatty liver disease, various malignancies (Table 7.2), gallstones, subfertility, musculo-skeletal problems and depression. 

Reduction in risk of Ml, stroke, and death from cardiovascular causes - In patients 55 years of age or older at high risk of developing a major cardiovascular event because of a history of coronary artery disease, stroke, peripheral vascular disease, or diabetes that is accompanied by at least 1 other cardiovascular risk factor (eg, hypertension, elevated total cholesterol levels, low FIDL levels, cigarette smoking, documented microalbuminuria). 

Coronary heart disease is one of the leading causes of death in the industrialized world (Packer, 1992 Remme and Swedberg, 2001). Hypertension is a risk factor for cardiovascular disease and is associated with an increased incidence of stroke and coronary heart disease. Other risk factors for cardiovascular disease include also high cholesterol, diabetes, and obesity. Although there have been many advances in treatment over the past several decades, less than a quarter of all hypertensive patients have their blood pressure adequately controlled with available therapies. 

Older patients have predominantly Type 2 diabetes mellitus, which shares with Type 1 the risk for retinopathy, nephropathy and neuropathy, but carries a greater risk for macrovascular complications such as coronary artery disease, stroke and peripheral vascular disease. Many such patients have associated obesity, hypertension and hyperlipidemia, compounding the risk of cardiovascular disease. The goals of treatment of DM in the elderly are to decrease symptoms related to hyperglycaemia and to prevent long-term complications. Treatment of type 2 DM can improve prognosis. In the UKPDS trial, sulphonylureas, insulin, and metformin were all associated with a reduction in diabetes-related... 

---