Streptomyces platensis

S. cerevisia NC 1299 Streptomyces platensis NRRL 2364 Ps. aeruginosa ATCC 10145... 

Streptomyces griseolus Streptomyces platensis Streptomyces rimosus Streptomyces roseochromogenus Streptomyces rimosus... 

N-demethylation, hydration N-demethylation of the nitrile group Streptomyces platensis)... 

Sakai T, Sameshima T, Matsufuji M, Kawamura N, Dobashi K, Mizui Y. (2004) Pladienolides, new substances from culture of Streptomyces platensis Mer-11107.1. Taxonomy, fermentation, isolation and screening. J Antibiot (Tokyo) 57 173-179. 

Two years later, the same authors also reported the 3 -epimer of RK-286C, RK-1409B (319), from the culture broth of Streptomyces platensis subsp. malvinus RK-1409. In nature, this isolate was obtained in its optically active form [a] + 147.0 (c 0.2, DMSO). RK-1409B showed inhibition of PKC and weak antifungal activity (304). 

The molecule is produced by Streptomyces platensis, a bacterium isolated from a South African soil sample. ... 

Igarashi M, KinoshitaN, IkedaT, Kameda M, Hamada M, Takeuchi T (1997) Resormycin, a Novel Herbicidal and Antifungal Antibiotic Produced by a Strain of Streptomyces platensis I. Taxonomy, Production, Isolation and Biological Properties. J Antibiot 50 1020... 

C.-Y. Chen and Y.-C. Su, Amperometric L-glutamate sensor using a novel L-glutamate oxidase from Streptomyces platensis NTU 3304, Anal. Chim. Acta, 243 (1991) 9-15. 

Streptomyces hygroscopicus Streptomyces viridochromogenes Streptomyces roseosporus Streptomyces platensis Streptomyces fradiae... 

Discovery Pladienolides are 12-membered macrohdes isolated as an antitumor substance by cell-based hypoxia-induced gene expression assay from Streptomyces platensis Mer-11107 [1]. The structures of pladienolide B and D were determined as 1 and 2, respectively [2,3]. Total synthesis of pladienolide B [4] and biosynthetic gene cluster [5] is also reported. 

Sakai, T Asai, N., Okuda, A., Kawamura, N., Mizui, Y. (2004). Pladienolides, new substances from cnltnre of Streptomyces platensis Mer-11107 ... 

Machida, K., Arisawa, A., Takeda, S., et al. (2008). Organization of the biosynthetic gene clnster for the polyketide antimmor macrolide, pladienolide, in Streptomyces platensis Mer-11107. Biosci. Biotechnol Biochem., 72, 2946-2952. 

Argoudelis and Mizsak isolated this C-nucleoside from culture filtrates of Streptomyces platensis and found that its structure is l-methyl-5-()8-D-ribofuranosyl)uracil (11) by studying the IR, UV, H NMR, C NMR, and mass spectra of the nucleoside as well as those of its triacetate (76JAN818). 

Leustroducsins A, B and C (90-92), produced by Streptomyces platensis SANK 60191, induce the production of colony stimulating factors by bone marrow stromal cells (100) and are closely related to the phoslactomycins, metabolites of other Streptomyces species (2). 

A chiral amine-catalyzed transfer hydrogenation was recently employed successfully by Lear and co-workers to obtain a key intermediate for die total synthesis of (—)-platensimycin (245) (213). (—)-Platensimycin (245) was identified from Streptomyces platensis in 2006 (214, 215). Due to its impressive antibacterial properties, it has generated considerable interest within the scientific and medical communities as a potential powerful new therapy against dmg-resistant bacteria (214, 215). Accordingly, several (formal) total synthesis approaches have been... 

C9H15N3O5 245.235 Nucleoside-type antibiotic. Obt. from Streptomyces platensis var. clarensis and Micromonospora melanogenes. Antiviral agent, useful against herpes simplex. Also active against grampositive and -negative bacteria. Needles. Sol. H2O. 

C10H14N2O6 258.23 Prod, by Streptomyces platensis var. clarensis, also found in archaebacterial tRNA. Shows weak antiviral props. Needles (EtOH). Sol. H2O, MeOH, EtOH fairly sol. Me2CO poorly sol. hexane. 

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