Hygromycin Streptomyces hygroscopicus

Producers, Product Profiles, Genetics, and Biosynthesis of Hygromycin B (HYG-B). Hygromycin B (HYG-B Figure 2.27) was first described in 1953 as a product of Streptomyces hygroscopicus ssp. hygroscopicus DSM 40578 and... [Pg.94]

Zalacain, M. Malpartida, E Pulido, D. Jimenez, A. Cloning and expression in Escherichia coli of a hygromycin B phosphotransferase gene from Streptomyces hygroscopicus. Eur. J. Biochem., 162, 413-418 (1987)... [Pg.59]

In our work, we have been interested in the biosynthetic origins of hygromycin A, and in developing a complementary approach to synthetic efforts by engineering the production of hygromycin A analogs in Streptomyces hygroscopicus. [Pg.18]

Occurrence. D-Talose is obtained on hydrolysis of the antibiotic hygromycin B, which is produced by Streptomyces hygroscopicus.131,132 The configuration of the sugar is (3-pyranosic in this compound as well as in the antibiotic Destomycin A. [Pg.27]

Hygromycin. 5-Deoxy-5-[[3-[4-(<6-deoxy-d-D-arabino.hexo/ttranos-S-ulos-l-yt)oxy]-3-hydroxyphenyl]-2-methyl-I-oxo-2-propenyt]amino]-l,2-0-methylene-D-neo-inositol homomycin hygromycin A 1703-18B St-4331. C23Hj,NO mol wt 511.47. C 54.01%. H 5.71%, N 2.74%. O 37.54%. Antibiotic substance produced by Streptomyces hygroscopicus (Jensen) Waksman Henrici, from forest soil near Indianapolis, Ind R L. Mann ef of.. Antibiot. ... [Pg.771]

W. (2002) An engineered Streptomyces hygroscopicus aph 7" gene mediates dominant resistance against hygromycin B in Chlamydomonas reinhardtii. Protist, 153 (4), 401 -412. [Pg.633]

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