Steroids Corticosteroids

Anabolic steroids Corticosteroids Male sex hormones Female sex hormones Oral fertility agents... 

Ho, E.N.M., Leung, D.K.K., Wan, T.S.M. and Yu, N.H. (2006) Comprehensive Screening of Anabolic Steroids, Corticosteroids, and Acidic Drugs in Horse Urine by Solid-Phase Extraction and Liquid Chromatography-Mass Spectrometry. J Chromatopfr A, 1120, 38. 

Several biologic ligands are sufficiently lipid-soluble to cross the plasma membrane and act on intracellular receptors. One class of such ligands includes steroids (corticosteroids, mineralocorticoids, sex steroids, vitamin D), and thyroid hormone,... 

There are many types of steroid hormones in the body, such as the sex/gonadal hormones testosterone and estrogen, thyroid hormones, growth hormones, and stress hormones, which serve various normal functions. One type of steroid— corticosteroids or glucocorticoids—is secreted by the adrenal glands (located just above the kidneys). These steroids, particularly synthetic versions of them, have powerful antiinflammatory actions that help to relieve pain. They are often given as an epidural injection to relieve neck or back pain that results from a compressed or pinched nerve. They can also be injected directly into a joint to relieve pain caused by inflammation in conditions such as tendonitis (inflammation of the tendons), carpal tunnel syndrome, tennis elbow, bursitis (inflammation of sac-like cavities in tendons or muscles that allow them to slide easily over bone), or other joint pain. Professional athletes, who routinely experience one or more of these conditions, are often given local steroid injections. Frequently, the steroid is combined with a local anesthetic such as lidocaine. 

Molecular imprinting [1] is now an established technique for the creation of polymeric matrices with predetermined affinity for particular substrates. The technique has been used for the creation of substrates with affinities for amino acids, peptides, proteins, nucleotides and nucleosides, carbohydrates, various drugs (e.g. opiates, alkaloids, antibiotics, /1-blockers, tranquillisers) and other bioactive compounds (e.g. enkephalin, steroids, corticosteroids), herbicides, pesticides, as well as metal ions and a number of miscellaneous organic compounds [2-5]. 

Cytochrome P450 isoz3mies Oxidation of steroids Corticosteroid biosynthesis... 

Diphenyl-3-(4-styrylphenyl)-tetrazolium chloride (TPTZ) for reducing steroids (corticosteroids). 

Hundreds of distinct steroids have been found in plants, animals, and microorganisms, respectively, for example, phytosterols and brassinosteroids in plant, ecdysteroids in insect, cholesterol, sex steroids, corticosteroids and anabolic steroids in vertebrate, and ergosterols in microorganism. Up to now, more than 40 steroid drugs have been marketed since the research and development to steroid drugs was triggered in 1950s [6, 7]. 

As has happened with GC-MS, there is a clear trend that the use of LC-MS, because of the increasing availability of robust and sensitive instruments, will be very common in the field of the analysis of growth promoters and endocrine disrupters. In many laboratories, LC-MS is used already to detect and identify anabolic steroids, corticosteroids, and p-agonists at low (Ag/L or lig/kg levels. Looking at multiresidue analysis, LC-MS will earn its position as a very useful technique. The development of quality criteria for LC MS, similar to the well-known criteria for GC-MS, for confirmatory analysis will certainly boost the possibilities for more general use. 

D. is the most suitable starting material for the production of - steroids (corticosteroids and contraceptives). 

Anabolic Androgenic Steroids/Corticosteroids/Hormone Antagonists and Modulators... 

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