Staphylococcus pyogenes

The dimaleate salt of 5,5-dimethyl-10-(4-methylpiperazino)-10,ll-dihydro-5H-dibenzo[b,/]silepin (45c) exhibited some antibacterial activity in vitro toward Mycobacterium tuberculosis H37Rv (minimum inhibitory concentration 12,5/igml ), Streptococcus -haemolyticus (25/igml ) and Staphylococcus pyogenes aureus (25/igml ) (76CCCC910). 

Staphylococcus pyogenes aureus.... . Boils, abscesses, carbuncles... 

Wachstum von Staphylococcus pyogenes aureus. Recueil Trav. chim. Pays-Bas 57, 747 (1938). 

PANI-g-chitosan (CS) has been screened for its antimicrobial activity against Staphylococcus epidermidis. Staphylococcus aureus. Staphylococcus pyogenes, Escherichia coli, Candida albicans, Candida tropicalis and Candida krusei. The results of the antimicrobial activity of PANI and PANI-g-CS were assessed based on the average diameter of zones of inhibition (ZOI). The results confirmed that PANI-g-CS has an enhanced antimicrobial activity compared with PANI. PANI and PANI-g-CS also show greater antifungal activity than antimicrobial activity [21]. 

Streptococcus pyogenes Streptococcusfaecalis and Staphylococcus aureus show a markedly greater susceptibihty to its action than Escherichia coli and Pseudomonas aeruginosa (205). Thiram has been used ia disiafectant soaps. 

Bacterial resistance to antibiotics has been recognized since the first drugs were introduced for clinical use. The sulphonamides were introduced in 1935 and approximately 10 years later 20% of clinical isolates of Neisseria gonorrhoeae had become resistant. Similar increases in sulphonamide resistance were found in streptococci, coliforms and other bacteria. Penicillin was first used in 1941, when less than 1 % of Staphylococcus aureus strains were resistant to its action. By 1947,3 8% of hospital strains had acquired resistance and currently over 90% of Staph, aureus isolates are resistant to penicillin. Increasing resistance to antibiotics is a consequence of selective pressure, but the actual incidence of resistance varies between different bacterial species. For example, ampicillin resistance inEscherichia coli, presumably under similar selective pressure as Staph, aureus with penicillin, has remained at a level of 30-40% for mai years with a slow rate of increase. Streptococcus pyogenes, another major pathogen, has remained susceptible to penicillin since its introduction, with no reports of resistance in the scientific literature. Equally, it is well recognized that certain bacteria are unaffected by specific antibiotics. In other words, these bacteria have always been antibiotic-resistant. 

The majority of SSTIs are caused by gram-positive organisms and, less commonly, gram-negative bacteria present on the skin surface. Staphylococcus aureus and Streptococcus pyogenes account for the majority of SSTIs. Community-associated methicillin-resistant S. aureus (CA-MRSA) has recently emerged and it is often isolated in otherwise healthy patients. 

Staphylococcus aureus, Haemophilus influenzae, Streptococcus pyogenes and Pseudomonas aeruginosa are all microorganisms that can cause otitis media. Enterobius vermicularis is a threadworm leading to an infection characterised by itchy anus and the presence of white worms. 

Moderate to severe uncomplicated skin and skin structure infections caused by Staphylococcus aureus or Streptococcus pyogenes. 2glV q 12 h 10... 

In mice infections with pneumococci were influenced very satisfactorily by aristolochic acid I. Rats with wounds infected with Staphylococcus aureus were treated intraperitoneally or orally with aristolochic acid I compared to controls, the treated animals recovered much faster. Rabbits after intravenous application of aristolochic acid I showed an increased antibactericial action of serum (97). Mice infected with bacteria including Staphylococcus aureus, Diphococcus pneumoniae, and Streptococcus pyogenes could be protected by treatment with 50 xg/kg ip of aristolochic acid I (97). 

Staphylococcus aures (penicillin-sensitive) Staphyloccocus aureus (penicillin-resistant) Streptococcus pyogenes Streptococcus pneumoniae Enterococcus faecalis ... 

Skin/skin structure infections Furunculosis, pyoderma and impetigo due to Staphylococcus aureus, S. pyogenes or S. agalactiae. 

Gram-positive (aerobes) Cocci Streptococci, e.g. Streptococcus pyogenes Staphylococci, e.g. Staphylococcus aureus Bacilli Listeria... 

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