Soulamea soulameoides

Simaroubaceae 15 a. Brucea javanica (57-59) 15b. Castela texana 60) 15c. Hannoa klaineana 61) 15d. Simaba multiflora 56, 62) 15e. Soulamea soulameoides (56)... 

Arisawa M, Handa SS, McPherson DD, Lankin DC, Cordell GA, Fong HHS, Farnsworth NR (1984) Plant Anticancer Agents. XXIX. Cleomiscosin A from Simaba multiflora, Soulamea soulameoides and Matayba arborescens. J Nat Prod 47 300... 

A series of six quassinoids isolated from Simaba multiflora and Soulamea soulameoides were shown to be active as growth inhibitors and as antifeedants against Heliothis virescens (cotton budworm) and Spodoptera frugiperda (fall armyworm) (Klocke et al., 1985). 

Several quassinoids are known to have antileukemic activity (Blasko and Cordell, 1988 Cordell, 1978 Polonsky, 1983). Only compounds with a C20 skeleton have antileukemic activity. Quassimarin (51) from Quassia amara and bruceoside A (52) from Brucea javanica and a series of other quassinoids from Brucea antidysenterica (all Simarou-baceae) (Fig. 25.12) are active in this regard. Bruceantin (53) has a high degree of antitumor activity in P-388, LE, LL and B16 tissue culture systems (Cordell, 1978). Six quassinoids from Simaba multiflora and Soulamea soulameoides were shown to be active against several mmor systems (Klocke et al., 1985). 

Arisawa M, Handa S S, McPherson D D, Lankin D C, Cordell G A, Fong H H S, Farnsworth N R 1984 Cleosmine A from Simaba multiflora, Soulamea soulameoides, and Matayba arbores-cens. J Nat Prod 47 300-307... 

Handa SS, Kinghorn AD, Cordell GA, Farnsworth NR 1983 Plant anticancer agents. XXV. Constituents of Soulamea soulameoides. J Nat Prod 46 359-364... 

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