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Sonic hedgehog signaling pathway

Finally, recent research has indicated that other human diseases, such as the commonest form of skin cancer, basal cell carcinoma, are caused by mutations in genes involved in the Sonic hedgehog signalling pathway. The Patched (Ptc) gene encodes a Sonic hedgehog receptor [92,93] and a tumor suppressor protein that is defective in basal cell nevus syndrome [94]. [Pg.585]

Gold, D. A., Baek, S. H., Schork, N. J., Rose, D. W., Larsen, D. D., Sachs, B. D., Rosenfeld, M. G., and Hamilton, B. A. (2003) RORalpha coordinates reciprocal signaling in cerebellar development through sonic hedgehog and calcium-dependent pathways. Neuron 40, 1119-1131. [Pg.314]


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Hedgehog signaling

Hedgehog signaling pathway

Pathway signalling

Signal pathways

Signaling pathway

Sonic hedgehog pathway

Sonic hedgehog signaling

Sonication

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