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Somatotropin release-inhibiting factor

Somatostatin (SS) = somatotropin-releasing inhibiting factor (SRIF). [Pg.202]

Somatostatin (or somatotropin release-inhibiting factor [SRIF]) occurs primarily as a 14-amino acid peptide, although a 28-amino acid form also exists. As with the other hypothalamic peptides, it is formed by proteolytic cleavage of a larger precursor. Somatostatin, originally isolated from the hypothalamus, is also in many other locations, including the cerebral cortex, brainstem, spinal cord, gut, urinary system, and skin. Somatostatin inhibits the secretion of many substances in addition to growth hormone (Table 59.1). [Pg.681]

Bruns, C Lewis, I., Briner, U., Meno-Tetang, G and Weckbecker, G. (2002) SOM230 a novel somatostatin petidomimetic with broad somatotropin release inhibiting factor (SRIF) receptor binding and a unique antisecretory profile. Eur. J. Endocrin. 146,707-716. [Pg.9]

Somatotropin release inhibiting factor) receptor (SRIF-R) ... [Pg.227]

SRIF-R, somatostatin (somatotropin release inhibiting factor) receptor SRP, signal recognition particle S-S, disulphide... [Pg.846]

Somatostatin Somatotropin release inhibiting factor (SRIF) displays antimitotic effects regarding various non-endocrine tumours. In animal experiments, octreotide retards tumour growth. The subcutaneous administration of octreotide (250 gg, 2x/day) resulted in a considerable improvement in survival time and quality of life. (93) There are still no clinical results available regarding the use of lanreotide, which has a longer action time. [Pg.786]

R. Guillemi, Isolation of Somatostatin (a somatotropin-release-inhibiting-factor) of ovine hypothalamic origin, Can.]. Biochem. 1974, 52,1067-1072. [Pg.268]

Somatostatin [somatotropin release inhibiting factor (SRIF), Ala-Gly-cyclo(Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys)] is a hypothalamic hormone that inhibits the release of growth hormone, insulin, and glucagon. Somatostatin is believed to adopt an overall p-sheet conformation with a... [Pg.44]

Somatostatin SOM SST14 SST28 Somatotropin release inhibitory factor (SRIF) Growth hormone release-inhibiting factor... [Pg.1147]

Growth hormone-releasing hormone (GHRH) (+) Somatotropin release-inhibiting hormone (SRIH, somatostatin) (-) Growth hormone (somatotropin, GH) Liver Insulin-like growth factors (IGF, somatomedins)... [Pg.850]

Statins, release inhibiting factors, release inhibiting hormones, neurohormones synthesized in the small-cell region of the hypothalamus and transported via the bloodstream to the anterior pituitary. Members of the statins include melanostatin, somatostatin, and prolactostatin. They inhibit the secretion of melanotropin, somatotropin, and prolactin, respectively. Together with the corresponding liberins, the statins regulate the levels of the three pituitary hormones. [Pg.355]

See other pages where Somatotropin release-inhibiting factor is mentioned: [Pg.203]    [Pg.167]    [Pg.846]    [Pg.986]    [Pg.259]    [Pg.260]    [Pg.1968]    [Pg.56]    [Pg.288]    [Pg.1373]    [Pg.212]    [Pg.350]    [Pg.203]    [Pg.167]    [Pg.846]    [Pg.986]    [Pg.259]    [Pg.260]    [Pg.1968]    [Pg.56]    [Pg.288]    [Pg.1373]    [Pg.212]    [Pg.350]    [Pg.1746]    [Pg.1970]    [Pg.313]    [Pg.833]    [Pg.812]    [Pg.197]    [Pg.702]    [Pg.703]   
See also in sourсe #XX -- [ Pg.167 , Pg.227 , Pg.228 ]



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