Sodium perborate oxidant

Sodium perborate oxidation of alcohols by is aided by Aliquat, but also requires the addition of chromium oxide [17]. However, the long reaction times at 60-80°C and the variable yields do not make the procedure particularly attractive. In contrast, direct epoxidation of a,p-unsaturatcd ketones has been conducted with moderate success using sodium perborate catalysed by tetra-n-hexylammonium hydrogen sulphate [18, 19]. 

Applications of oxaziridine rearrangements in asymmetric syntheses have been reviewed,596 and the formation of A,A-disubstituted formamides (462) on sodium perborate oxidation of alkyl A-arylaldimines (460) has been rationalized597 in terms of an intermediate oxaziridine (461) that rearranges via acid-catalysed O—N cleavage. 

SODIUM PERBORATE OXIDATION OF ORGANOBORANES a Alkene Reagent Product Yield(%)b... 

With acetic acid as solvent, sodium perborate oxidizes p-substituted derivatives of aniline to azobenzenes at temperatures of 35-60°. An example is formulated ... 

A number of anilines have been oxidized with the same reagent in AcOH (50-60 °C, 1.5-2 h) to afford nitroarenes in 47-92% yields (Scheme 118) ° . 4-Methoxy- and 4-cyanoanilines (618 and 619) underwent sodium perborate oxidation in AcOH to the corresponding nitroarenes 620 and 621 in 70 and 91% yields, respectively. 

Autocatalysis in the sodium perborate oxidation of anilines in acetic acid-ethylene glycol. J. Mol. Catal. A Chem., 172, 9-17. 

The kinetics of oxidation of aniline by sodium perborate catalysed by the meso-tetraphenylporphyriniron(III) chloride reveal that the catalyst is slowly degraded. The retardation in the rate with increasing H+ ions suggests that the protonated aniline is less reactive. Sodium perborate oxidation of several meta- and puru-substituted anilines complies with isokinetic and Exner relationships but not to any of the linear free energy relationships. The solvent interaction has a major role in governing the reactivity. ... 

The sodium perborate oxidation of morpholine and A-methylmorpholine is first order in the oxidant and substrates peroxoborate anion acts as the oxidizing species... 

Detecting the presence of small, even invisible, amounts of blood is routine. Physical characteristics of dried stains give minimal information, however, as dried blood can take on many hues. Many of the chemical tests for the presence of blood rely on the catalytic peroxidase activity of heme (56,57). Minute quantities of blood catalyze oxidation reactions between colorless materials, eg, phenolphthalein, luco malachite green, luminol, etc, to colored or luminescent ones. The oxidant is typically hydrogen peroxide or sodium perborate (see Automated instrumentation,hematology). 

Neutralizing Lotion. The principal active ingredient of cold wave neutralizers is usually an oxidizing agent. The most popular is hydrogen peroxide [7722-84-1J, employed at a concentration of 1—2% it continues to find widespread use. Aqueous solutions of sodium bromate [7789-38-0] at a concentration of 10—20% occasionally are used and are technically preferred over the peroxide formulations because of excellent stabiUty and absence of hair bleaching. Neutralizing powders appear to be on the decline but formulations stiU in use consist of sodium perborate [7632-04-4] combined with hexametaphosphates to improve solubiUty in hard water. 

In a related reaction, primary aromatic amines have been oxidized to azo compounds by a variety of oxidizing agents, among them Mn02, lead tetraacetate, O2 and a base, barium permanganate, and sodium perborate in acetic acid, tert Butyl hydroperoxide has been used to oxidize certain primary amines to azoxy compounds. 

All classes of primary amine (including primary, secondary, and tertiary alkyl as well as aryl) are oxidized to nitro compounds in high yields with dimethyl dioxirane." Other reagents that oxidize various types of primary amines to nitro compounds are dry ozone, various peroxyacids," MeRe03/H202,"" Oxone ," ° tcrt-butyl hydroperoxide in the presence of certain molybdenum and vanadium compounds, and sodium perborate." ... 

Many other peroxy compounds can analogously be produced in the region of HAP for instance, sodium perborate Na2(B03)2 (from sodium metaborate NaB02) and peroxycarbonates. These compounds are used as stable oxidizing and bleaching agents. 

The instability of DAST-type brighteners towards chlorine-containing bleaches has been mentioned already. They also show limited stability towards per-acids. As recommended washing temperatures have tended to fall in recent years, a bleach consisting of sodium perborate activated by addition of tetra-acetylethylenediamine (11.63) has become an important component of household detergent formulations. This system is effective at temperatures as low as 40-50 °C. Since the FBA may be sensitive to the activated oxidant, however, in some formulations it is necessary to protect compounds such as 11.60 or 11.61 by encapsulating either the brightener or the activator, if adequate shelf-life is to be maintained. 

Hazards attendant on the use of this powerful oxidant may in many cases be eliminated by substitution with sodium perborate (actually sodium borate hydrogen peroxidate) [1]. One of several wooden boxes of the peroxide (not clearly labelled as such) exploded with great violence dining handling operations. It seems likely that contamination with a combustible material, or possibly with moisture, had occurred [2],... 

Various convenient methods for the oxidation of oximes to nitro compounds have been developed in recent years. Olah has reported a convenient oxidation of oximes to nitro compounds with sodium perborate in glacial acetic acid (Eq. 2.60).122... 

A Simple and Convenient Method for the Oxidation of Organoboranes Using Sodium Perborate Preparation of (+)-Isopinocampheol. 

For analysis in solutions, the most frequently used CL reaction is alkaline oxidation of luminol and lucigenin in the presence of hydrogen peroxide as oxidant, although sodium hypochlorite, sodium perborate, or potassium ferricyanide may also be used. CL reactions involving alkaline oxidation have been used to indicate acid-base, precipitation, redox, or complexometric titration endpoints either by the appearance or the quenching of CL when an excess of titrant is present [114, 134], An example of these mechanisms is shown in Figure 14. 

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