Cellulose sodium glycolate

CMC. Designation for Carboxymethy I-cellulose. Sodium Salt, known also as Sodium Cellulose Glycolate,... 

FINE GUM HES GLIKOCEL TA KMTS 212 LOVOSA LUCEL (polysaccharide) MAJOLPLX MODOCOLL 1200 NACM-CELLULOSE SALT NYMCEL S POLYFIBRON 120 SANLOSE SN 20A SARCELL TEL S 75M SODIUM CELLULOSE GLYCOLATE SODIUM CMC SODIUM CM-CELLULOSE SODIUM SALT of CARBOXYMETHYL-CELLULOSE TYLOSE 666 UNISOL RH... 

Akucelh, Aquasorb-, Blanose cellulose gum CMC sodium E466 Finnfix, Nymceb, SCMC sodium carboxymethylcellulose sodium cellulose glycolate sodium CMC Tylose CB. 

NaCMC is frequently designated as sodium cellulose glycolate and under a purified form as cellulose gum. An acidic form (non-neutralized) of CMC is also commercially available. 

Sodium Carbozymethylcellulose (Sodium CMC) (Sodium Cellulose Glycolate). 

Synonyms Carbor ethylcellulose Carbor ethylcellulose, sodium salt Carboxymethyl ether cellulose sodium salt Cannellose sodium Cellulose carboxymethyl ether Cellulose carbor methyl ether sodium salt Cellulose glycolic acid sodium salt Cellulose gum (INCI) Cellulose, polyanionic Cellulose sodium glycolate CMC CMC sodium salt NaCMC SCMC Sodium carboxymethylcellulose Sodium cellulose glycolate Sodium CMC Sodium CMSodium salt of the polycarbot ethyl ether of cellulose Fornujia RnOCHjCOONa... 

CMC CMC sodium salt NaCMC SCMC Sodium carboxymethylcellulose Sodium cellulose glycolate Sodium CMC Sodium CM-cellulose... 

Sodium cellulose glycolate. See Carboxymethylcellulose sodium Sodium cellulose sulfate CAS 9005-22-5... 

The resultant yellow sodium cellulose xanthate is dispersed in an aqueous caustic soda solution, where some hydrolysis occurs. This process is referred to as ripening and the solution as viscose . When the hydrolysis has proceeded sufficiently the solution it transferred to a hopper from which it emerges through a small slit on to a roller immersed in a tank of 10-15% sulphuric acid and 10-20% sodium sulphate at 35-40°C. The viscose is coagulated and by completion of the hydrolysis the cellulose is regenerated. The foil is subsequently washed, bleached, plasticised with ethylene glycol or glycerol and then dried. 

Although untreated starches do not swell sufficiently, certain modified forms, such as sodium starch glycolate, do swell in cold water and are better as disintegrants. Various cellulose derivatives, including methylcellulose and carboxymethylcellulose, have been used in this role, but with limited success due to the marked increase in viscosity they produce around the dispersing tablet mass. 

It is a yellow solid with a solubility in water of 0.007 mg/mL. The Tykerb tablet contains 405 mg of the active ingredient, and the inactives are magnesium stearate, microcrystalline cellulose, povidone, and sodium starch glycolate. 

Corboxymethylcellulose(CMC). A cellulose glycolate compd that has achieved great coml importance in recent years. The Sodium salt is its most important deriv col, odorless, tasteless, non-toxic, hygro powd combustible when finely ground. The trademark for one tech grade coml product is "Carbose (Ref 2). 

This substance, curiously, was referred to as cellulose glycolic acid in the earlier literature, though it might have been appropriately termed cellulose acetic acid. It is referred to herein as carboxymethylcellulose, although, in many cases, the sodium salt is actually the substance under discussion. This review summarizes the literature on the chemistry and uses of carboxymethylcellulose up to the present. 

Povidone, hydroxypropyl cellulose, hypromellose Crospovidone, sodium starch glycolate, sodium croscarmellose Talc, silicon dioxide... 

Croscarmellose sodium. Microcrystalline cellulose. Calcium hydrogen phosphate. Sodium starch glycolate. 

Fig. 16 Disintegrants. Primojel (A), Explotab, sodium starch glycolates (B), cross-linked carboxymethyl cellulose (C), and calcium carboxymethyl cellulose (D).

A fiber optic probe was used by Blanco et al. for analysis of spasmoctyl samples with the active compound otilonium bromide and cellulose, maize starch, sodium starch glycolate, and glyceryl palmitostearate as excipients. Another study from this group covered the identification, qualification of the substance, and the quantification of the active component. A library search with a comparison to the near-infrared spectra of 163 pharmaceuticals was involved. An on-line monitoring for the determination of the endpoint of polymorph conversions in pharmaceutical processes was recently described further investigations into this field were published and are noted previously. ... 

Cellulosics sodium carboxymethylcellulose, microcrystalline cellulose (including coprecipitates and blends of the two), hydroxyethylcellulose, hydroxy-propyl cellulose, hydroxypropyl methylcellulose, methylcellulose, starch, sodium starch glycolate, and powdered cellulose... 

Analysis of the coefficients indicates that the drug is relatively unstable when formulated. Formulations containing cellulose are less stable than those with lactose and sodium starch glycolate has a deleterious effect on stability compared with starch. There appears to be no difference between the lubricants and the binders tested and the presence of colloidal silica has no effect on the stability. 

Cellulose gel. See Microcrystalline cellulose Cellulose glycolic acid sodium salt Cellulose gum. See Carbor methyl-cellulose sodium... 

Cellulose sodium glycolate. See Carboxymethylcellulose sodium Cellulose tetranitrate. See Nitrocellulose... 

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