SOCs synthetic

PCR Pol) merase Chain Reaction SOC Synthetic Organic Compounds... 

M. Bodansky, Peptide Synthesis, 2nd ed., John Wiley Sons, Inc., New York, 1976 J. Meinhofer in Ref. 1, Chapt. 9, p. 297 G. R. Pettit, Synthetic Peptides, Vols. 1—4, Van Nostrand Reinhold, New York, 1980, Vols. 5, 6, Elsevier New York, 1982 E. Shroeder and K. Luebke, The Peptide, Vol. 1, Methods of Peptide Synthesis, Academic Press, New York, 1965 N. Izumiya and co-workers. Fundamentals and Experiments of Peptide Synthesis (in Japanese), Mamzen, Tokyo, Japan, 1987 R. B. Merriheld,/ Mm. Chem. Soc. 85, 2149 (1963) G. Barany and R. B. Merriheld in E. Gross andj. Meinenhofer, eds.. The Peptides Mnalysis, Synthesis, Biology, Vol. 2, Academic Press, New York, 1980, pp. 1—284 G. R. Marshall, Peptides Chemistry and Biology, Escom, Leiden, The Netherlands, 1988. 

It has been recrystd from H2O (fine needles) and is freely soluble in boiling H2O. Crysts also from H2O by addition of acetone. Purified by chromatography on Dowex 1 (in formate form), eluting with 0.25M formic acid. It was then adsorbed onto charcoal (which had been boiled for 15min with M HCI, washed free of chloride and dried at 100°), and recovered by stirring three times with isoamyl alcohol/H20 (1 9 v/v). The aqueous layer from the combined extracts was evaporated to dryness under reduced pressure, and the product was crystallised twice from hot H2O. [Morrison and Doherty Biochem J19 433 7967]. It has A-max 259nm (e 15,400) in H2O at pH 7.0. [Alberty et al. J Biol Chem 193 425 7957 Martell and Schwarzenbach Heh Chim Acta 39 653 7956]. The acridinium salt has m 208° [Baddiley and Todd J Chem Soc 648 1947 Pettit Synthetic Nucleotides, van Nostrand-Reinhold, NY, Vol 1 252 1972 NMR Sarma et al. J Am Chem Soc 96 7337 1974 Norton et al. J Am Chem Soc 98 1007 1976 IR of diNa salt Miles Biochem Biophys Acta 27 324 1958],... 

Compound A possesses the structure originally proposed for the methyl ester of Aao (see K. Nakanishi, M. Endo, U. Naf, and L. F. Johnson, J. Am. Chem. Soc, 1971, 93, 5579). However, the 270-MHz NMR spectrum of synthetic A was different from that reported for Aah methyl ester with respect to the protons at C(3) and C(5). Therefore, the 3a-alcohol, compound B, was synthesized as shown below. 

Fmlfaerexamplesof the ingenious use of Grignaid reagents will be found in many books on synthetic organic chemistry and much recent work in this area was reviewed in a special edition of Bull. Soc. Chim. Franct, 1972, 2127-86, which commemorated the centenary of Victor Grignaid s biith. 

Metal clusters in biology quest for a synthetic representation of the catalytic site of nitrogenase. R. H. Holm, Chem. Soc. Rev., 1981,10, 455-490 (137). 

Dias L. C. Chiral Lewis Acid Catalysts in Diels-Alder Cycloadditions Mechanistic Aspects and Synthetic Applications of Recent Systems J. Braz. Chem. Soc. 1997 8 289-332... 

Taguchi H, Yokoi T, Tsukatani M, Okada Y (1995) Tetrahedron 27 7361 Vekemans J, Pollers-Wieers C, Hoornaert G (1983) J Heterocyclic Chem 20 919 Tutonda M, Vanderzande D, Hendrickx M, Hoornaert G (1990) Tetrahedron 46 5715 Deceuninck JA, Verschave P, Buffel DK, Tutonda M, Hoornaert G (1991) In Townsend LB, Stuart Tipson R (eds) Nucleic acid chemistry, improved and new synthetic procedures, methods and techniques. Wiley, New York, p 144 Buysens KJ, Vandenberghe DM, Toppet SM, Hoornaert GJ (1996) J Chem Soc Perkin Trans 1 231... 

Hanby WE, Waley SG, Watson J (1948) Synthetic polyglutamic acid. Nature 161 132 Hanby WE, Waley SG,Watson J (1950) 632. Synthetic polypeptides. Part n. Polyglutamic acid. J Chem Soc 3239-3249... 

Brack A, Spach G (1981) Multiconformational synthetic polypeptides. J Am Chem Soc 103 6319-6323... 

Corey EJ, Wipke WT, Cramer RD HI, Howe WJ. Computer-assisted synthetic analysis. Facile man-machine communication of chemical structure by interactive computer graphics. J Am Chem Soc 1972 94 421-30. 

Gobrecht J, Tributsch H, Gerischer H (1978) Performance of synthetical n-MoSc2 in electrochemical solar cells. J Electrochem Soc 125 2085-2086... 

Ennaoui A, Eiechter S, Goslowsky H, Tributsch H (1985) Photoactive synthetic polycrys-taUine pyrite (PeS2). J Electrochem Soc 132 1579-1582... 

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