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Skin, human, properties

Numerous reports exist to suggest that application of therapeutic ultrasound (1-3 MHz, 0-2W/cm ) does not induce any irreversible change in the skin permeability to drugs in vivo. Quantitative measurements of estradiol transport across human skin (in vitro) have also shown that application of therapeutic ultrasound (1 MHz, 2W/cm ) does not induce any statistically significant irreversible change in skin barrier properties. Similar studies have also been performed using very low-frequency ultrasound (20 kHz, 125mW/cm, 100 ms pulses applied every second) to assess whether... [Pg.3839]

The stratum corneum layer of nonwetted human skin is strongly variable and may be very poorly conductive. As we shall see, the skin is often dominating the electrical properties of an electrode used for recording endogenic signal sources such as the ECG. This skin influence is therefore treated here. For additional information on skin electrical properties, see Chapter 4. [Pg.185]

In BPl production, the recycling of spent catalyst, acids, glycol, and methanol contributes economical and environmental advantages [35]. Importantly, the handling of solid materials with possible skin sensitizing properties and toxicity is avoided, thereby eliminating human and environmental exposure. [Pg.378]

The HYBOT descriptors were successfully applied to the prediction of the partition coefficient log P (>i--octanol/water) for small organic componnds with one acceptor group from their calculated polarizabilities and the free energy acceptor factor C, as well as properties like solubility log S, the permeability of drugs (Caco-2, human skin), and for the modeling of biological activities. [Pg.430]

Fumaric Acid. Fumaric acid is used to acidify beverages for human consumption and has many iadustrial uses. Its acidic properties can cause skin and eye irritation. Fumaric acid combusts when exposed to heat or flame and can react vigorously with oxidizing agents. [Pg.459]

Skin tolerance was tested on rabbits. A 1 % alkanesulfonate solution applied five times did not produce any irritation on the rabbits skin. The same results were obtained by the closed patch test carried out with human test subjects in a hospital. The good dermatological properties were also confirmed by the Polano test (arm immersion test). [Pg.215]

What parts of your body are ionic compounds Those that compose your skin Your hair Actually, most of the human body is composed of nonionic compounds. But, you could not live without sodium chloride and other ionic compounds found inside you. How can you distinguish ionic compounds from other types of compounds By investigating sodium chloride, you will explore some of the common properties of ionic compounds. [Pg.57]

The oxidative polymerization of 5,6-dihydroxyindole (1) and related tyrosine-derived metabolites is a central, most elusive process in the biosynthesis of eumelanins, which are the characteristic pigments responsible for the dark color of human skin, hair, and eyes. Despite the intense experimental research for more than a century,36 the eumelanin structure remains uncharacterized because of the lack of defined physicochemical properties and the low solubility, which often prevents successful investigations by modem spectroscopic techniques. The starting step of the oxidative process is a one-electron oxidation of 5,6-dihydroxyindole generating the semiquinone 1-SQ (Scheme 2.7). [Pg.48]

Gender, too, affects the appearance of human skin. Nevertheless, there is little evidence that the skin of males and females differs greatly in permeability. However, there are established differences in the barrier properties of skin across the races of humans. While the horny layers of Caucasians and Blacks are of equal thickness, the latter has more cell layers and is measurably denser [30]. As a consequence, black skin tends to be severalfold less permeable [30,31],... [Pg.208]


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See also in sourсe #XX -- [ Pg.2 , Pg.68 ]




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