Site-readiness evaluation

The final task of the pre-installation process should be a preinstallation qualification. This is a site-readiness evaluation indicating whether the location into which the HPLC system is to be installed is actually ready to accommodate this system. This should include the following utility/spatial/environmental and safety considerations ... 

After method optimization the most important aspects of the validation are checked in a pre-validation study to examine whether the method is ready for evaluation at the customer site. If necessary, method optimization may need to be repeated. Suggested parameters to be... 

The chapter coordinators met over a three-year period to evaluate and revise various drafts of the document. Once the RO found the unedited final draft acceptable, it was sent to over 100 contact points throughout the world for review and comment. The unedited draft was also made available on the IPCS web site for external review and comment for a period of two months. These comments were peer-reviewed by the RO and chapter coordinators, and additions and revisions to the draft document were made if necessary. A file of all comments received and revisions made on the draft is available from the RO. When the RO was satisfied as to the scientific correctness and completeness of the document, it was forwarded to an IPCS editor for language editing, reference checking, and preparation of camera-ready copy. After approval by the Director, IPCS, the manuscript was submitted to the WHO Office of Publications for printing. It will also be available on the IPCS web site. 

The site conducts emergency preparedness drills and exercises to evaluate its readiness response to emergencies. An annual emergency drill is held onsite, in conjunction with state and local coimty emergency responders, as a training exercise to improve inter-agency coordination and commimication skills. 

Both interview and questionnaire techniques were used in this survey. Fifty, semi-structured interviews were conducted on-site with a randomly selected, representative, stratified sample of employees. (See Appendix B for an example of some of the prompt questions used in the interview note that this can only be developed after some open interviews/discussion sessions are completed.) A questiormaire was generated from the interview data and distributed to 520 staff to be completed anonymously. This produced a 45 per cent usable response rate for analysis. The objectives were to gain an understanding of the perceptions of quality within the company and readiness for change to provide baseline data for evaluation purposes to identify quality improvement opportunities and potential barriers to change and to help management develop a sense of awareness about quality and quality improvement needs in the plant. The questionnaire included measures of job satisfaction (Warr et aL, 1979), organizational commitment (Porter et al., 1974), perceptions of cooperation and morale in the plant and measures of certain job characteristics associated with quality work performance, such as skill variety, autonomy and feedback (Hackman and Oldham, 1975). 

Scale diagrams and maps need to include the following existing structures, property lines, entrances and exits, fire hydrants, sprinkler systans, emergency equipment, plant-controlled shut-offs, and hazardous material locations. These locations should be color-coded to ensure ready recognition. Scaled overlays should be drawn to show safe distances. The overlays can be placed over the point of incident to show the cordon area. However, because an incident can extend beyond site boundaries, the plot maps should cover all potential affected areas. This process helps evaluate risk to both the site and the community. 

A special kind of inspection often overlooked is the readiness check, where operations are evaluated for safety before work on them begins. Examples of situations where these inspection checks are appropriate include the setting up of tower cranes and other temporary works such as installation of falsework, preparation for excavations and facade support work. Two checklists at the end of this chapter are intended to give useful examples of readiness inspection checks for specific topics (Figs 3.3 and 3.4), and Fig. 3.5 provides a general site checklist. 

In correlation studies over large numbers of crystal structures, the calculation of the lattice energy must be relatively fast, and it is very difficult, if not altogether impossible, to calculate accurate point charges or distributed dipoles for thousands of molecules. It is also impossible to analyze all the molecular structures to find the locations of specific charge sites such as lone pairs, bond dipoles, etc. the formulation must be a strictly atom-atom one, with all interaction centers located at easily recognizable atomic nuclear positions, and should either require no separate coulombic terms, or use a ready recipe for the approximate evaluation of atomic point charge parameters without ab initio molecular orbital calculations. 

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