Sildenafil citrate

Involved in penile erection sildenafil citrate (Viagra) affects this process by inhibiting a cGMP phosphodiesterase... [Pg.574]

Viagra 25-100 mg (sildenafil citrate) One tab qd, one hour before sexual activity... [Pg.65]

Laties, A.M., Ellis, P, and Mollon, J.D., The effects of sildenafil citrate (Viagra ) on color discrimination in volunteers and patients with erectile dysfunction, Inv. Ophthalmol. Vis. Sci., 40, S693, 1999. [Pg.132]

Patients who are using certain drugs for erectile dysfunction (eg, sildenafil citrate), because these drugs have been shown to potentiate the hypotensive effects of organic nitrates (sublingual tablets, lingual spray, transdermal). [Pg.415]

A method is described for extraction and determination of sildenafil citrate and its metabolites in human serum by micellar electrokinetic capillary chromatography (MEKC) coupled with sample stacking and polarity switching <2002JCH279>. [Pg.611]

Since its approval by the FAD on 27 March 1998, it has been widely utilized and is available in 25, 50, and 100 mg tablets. Many techniques have been used to determine sildenafil citrate in pharmaceutical samples <2002TAL757, 2000JLC1377, 2003MI2897, 2001MI483>. A liquid chromatographic method to determine sildenafil in rat serum... [Pg.646]

Phosphodiesterase Type 5 (PDE5) inhibitors sildenafil citrate... [Pg.624]

Lee M, Min DI. Determination of sildenafil citrate in plasma by high-performance liquid chromatography and a case for the potential interaction of grapefruit juice with sildenafil citrate. Ther Drug Monit 2001 23(l) 21-26. [Pg.189]

Galie N et al Sildenafil citrate therapy for pulmonary arterial hypertension. N Engl 3 Med 2005 353 2148. [PMID 16291984]... [Pg.269]

The development of an environmentally benign synthesis of sildenafil citrate (Viagra ) and its assessment by green chemistry metrics. Green Chem. 6 (1) 43-48. [Pg.277]

USAN Sildenafil Citrate Trade Name Viagra Company Pfizer Launched 998 M.W. 474 58... [Pg.189]

Pfizer also received a Crystal Faraday Award for optimizing the process used to manufacture the active ingredient in Viagra , sildenafil citrate. Shown in Figure 3.6 is the solvent usage during each stage of process development for sildenafil citrate over a 15-year lime line [19]. [Pg.58]

Dunn, P. J., Galvin, S., Hettenbach, K. The Development of an Environmentally Benign Synthesis of Sildenafil Citrate (Viagra) and Its Assessment by Green Chemistry Metrics. Green Chem. 2004, 6, 43 18. [Pg.355]

For example, the citrate ion is commonly used as a counter ion for positively charged medications, e.g., sildenafil citrate (Viagra). [Pg.305]

Gillies HC, Roblin D, Jackson G. Coronary and systemic haemodynamic effects of sildenafil citrate from basic science to clinical studies in patients with cardiovascular disease. Int J Cardiol 2002 86 131-141. [Pg.512]

Padma-Nathan H (ed). Sildenafil citrate (Viagra) and erectile dysfunction a comprehensive four year update on efficacy, safety, and management approaches. Urology 2002 60(2B) 1-90. [Pg.512]

Mittleman MA, MacClure M, Glasser DB. Evaluation of acute risk for myocardial infarction in men treated with sildenafil citrate. Am J Cardiol 2005 96 443-446. [Pg.512]

Jackson G, Gillies H, Osterloh I. Past, present and future a 7-year update of Viagra (sildenafil citrate). Int J Clin Pract 2005 59 680-691. [Pg.512]

Fox KM, Thadani U, Ma PTS, et al. Sildenafil citrate does not reduce exercise tolerance in men with erectile dysfunction and chronic stable angina. Eur HeartJ 2003 24 2206-2212. [Pg.512]

After addition of citric acid to the 5-[2-ethoxy-5-(4-methylpiperidinylsulphonyl)phenyl]-l-methyl-3-n-propyl-l,6-dihydro-7H-pyrazolo[4,3-d]-pyrimidin-7-one (sildenafil) the it s salt is obtained, namely sildenafil citrate. [Pg.3036]

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