Silanes 3-aminopropyl triethoxysilane

Culler, S.R., Ishida, H. and Koenig, J.L. (1986). The silane interphase of composites effects of process condition on y-aminopropyl triethoxysilane. Polym. Composites 7, 231-238. 

Covalent immobilization methods of NAs to a silica surface require its chemical modification. Functionally inert surface silanols (Si - OH) need to be transformed into reactive species to which the NAs can be attached irreversibly. To date, the main method for the attachment of biological moieties to silica surfaces has involved substrate reaction with organofunctional silanes of the general structure (RO)3Si(CH2)X, followed by the covalent attachment of the biological molecule to the newly introduced fimctional group on the surface [31,32]. Examples of organofimctional silanes used this way include (3-glycidoxypropyl)trimethoxysilane, (3-aminopropyl)triethoxysilane,... 

Fig. 9 Silanization of silica siufaces with aminopropyl(triethoxysilane). In (i) the reactive groups of the triethoxysilane are hydrolyzed by water, followed by condensation (ii) with the surface and (iii) thermal curing of the film, which further cross-links the free silanol groups...

Amino silane solution Mix 45 mL methanol and 5 mL deionized water. Add one drop of acetic acid. To this, add 1 mL of 3-aminopropyl triethoxysilane (Gelest, Inc., Tullytown, PA). Prepare immediately before use. 

N-Ac-Trp-amide or fluorescein Bis(2-hydroxyethyl)aminopropyl-triethoxysilane tetraethoxysilane silica gel Organic silane based polymer [72]... 

CAS 919-30-2 EINECS/ELINCS 213-048-4 Synonyms (3-Aminopropyl) triethoxysilane y-Aminopropyl triethoxysilane Propylamine, 3-(triethoxysilyl)- Silane, (3-aminopropyl) triethoxy- Silane, y-aminopropyltriethoxy- Triethoxy (3-aminopropyl) silane 3-(Triethoxysilyl)-I -propanamine 3-(Triethoxysilyl) propylamine Empirical CgHjsNOsSi Formula NH2(CH2),Si(OC2H5),... 

Figure 3.8 The most frequently used methods to immobilize capture molecules onto microarray surfaces. (A) Antibody adsorption by poly-L-lysine-, nitrocellulose-, or polyvinylidene fluoride-treated surface. (B) Covalent binding using various silane reagents of APTES (3-aminopropyl)triethoxysilane, GPTS (3-gly-cidoxypropyl)trimethoxysilane, and MPTS (3-mercaptopropyl)trimethoxysilane. (C) Affinity interactions by biotin/streptavidine or histidine-tag/nickel-nitrilotri-acetic acid. (D) Diffusion-based (hydrogel) antibody-immobilization technique.

In siunmary, a three-step reaction procedure was employed to attach RGD-containing peptides onto a titanium surface. First, water-vapor-plasma-pretreated titanium surfaces were silanized with (3-aminopropyl)-triethoxysilane in dry toluene, resulting in a multilayer film of poly(3-aminopropyl)siloxane. Second, the free primary amino groups were linked to one of the three hetero-cross-hnkers AI-succinimidyl-6-maleimidylhex-anoate, iV-succinimidyl-3-maleimidylpropionate, and N-... 

Preparation of HRP Immobilized Substrate. A glass slide was dipped into a 10(3-aminopropyl)triethoxysilane/benzene solution for 8 h. A phosphate buffer solution containing a 530 units/ml HRP, a 1.7 mg/ml BSA, and a 0.8 % (vAr) GA was spotted on the silanized glass slide at intervals of 100 pm by a glass cs illary pen (tip radius, 20 pm). The substrate was then washed thoroughly with buffer solution. 

In peptide surface fabrication, the most commonly performed modification of glass surfaces is the attachment of molecules that display reactive functionalities such as amines, carboxylic acids, or aldehydes. Amine-terminated silanes such as (3-aminopropyl)triethoxysilane are typically used as the first step. Homobifunctional linkers, that is, linkers that have the same amine reactive group on both... 

Herlem, G., O. Segut, and A. Antoniou, 2008. Electrodeposition and characterization of silane thin films from 3-(aminopropyl)triethoxysilane. Surf. Coatings Technol 202 1437-42. 

Preparation of the stationary phase was performed by dissolving 0.75 g of amylose tnXcyclohexyl carbamate) in 10 ml of tetrahydrofuran. Macroporous silanized silica gel (3 g) [made from silica gel, Daiso Gel SP-1000, pore size 100 nm, particle size 7 /u-m, silanized using (3-aminopropyl)triethoxysilane in benzene at 80°C] was added to the solution and the resulting suspension was dried under vacuum. A portion of this material (1.5 g) and fluorescent indicator (Merck) (0.1 g) were mixed with methanol (3 ml). The slurry was applied to microslides (2.6 X 7.6 cm, thickness 0.3 mm) and the plates were dried in an oven at 110°C for 30 min [37]. 

In another work, silica nano helices have been prepared from the organic self-assemblies of -tartrate amphiphiles by sol-gel transcription. Then this chiral nanostructures were functionalized with (3-aminopropyl)-trietho)y-silane (APTES) or (3-mercaptopropyl)triethoxysilane (MPTES) and decorated with gold nanoparticles of various diameters (1-15 nm) resulting in nanohelix hybrid structures (Fig. 25). ° It was found that the surface plasmon resonance intensity of these nanohybrid systems increased with gold particle size. Gold nanoparticles of 10-14 nm diameter have clearly showed a surface enhanced effect on Raman spectroscopy. This sj tem is a unique example of the 3D hybrid network that could be used as ultrasensitive chemical and biological sensors for detection of molecules of interest in liquids by accumulation under flow. 

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