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Sex cord stromal tumor

Ovarian sex cord-stromal tumors account for about 5% of all ovarian cancers and tend to be diagnosed at stage I. ° These tumors are associated with hormonal effects, such as precocious puberty, amenorrhea, and postmenopausal bleeding. [Pg.2469]

Mostly Negative Germ cell tumors except choriocarcinoma, ovarian sex cord stromal tumors... [Pg.224]

Deavers MT, Malpica A, Liu J, et al. Ovarian sex cord-stromal tumors an immunohistochemical study including a comparison of calretinin and inhibin. Mod Pathol. 2003 16 584-590. [Pg.255]

Sasano H, Okamoto M, Mason JI, et al. Immunohistochemical studies of steroidogenic enzymes (aromatase, 17 alpha-hydroxylase and cholesterol side chain cleavage cytochrome P450) in sex cord stromal tumors of the ovary. Hum Pathol. 1989 20 452-457. [Pg.330]

McCluggage WG, Shanks JH, Whiteside C, et al. Immunohistochemical study of testicular sex cord-stromal tumors, including staining with anti-inhibin antibody. Am J Surg Pathol. 1998 22 615. [Pg.660]

Gordon MD, Gorless G, Renshaw AA, Beckstead J. CD99, keratin, and vimentin staining of sex cord-stromal tumors, normal ovary, and testis. Mod Pathol. 1998 11 769. [Pg.661]

TABLE 18.7 Endometrioid Carcinoma vs. Sex Cord Stromal Tumors ... [Pg.728]

Tumors derived from the sex cords or ovarian mesenchyme compose 5% to 12% of all ovarian neo-plasms. 413 Benign tumors in the fibroma-thecoma group are relatively common. Other sex cord-stromal tumors and mesenchymal tumors are rare. The most common malignant sex cord- stromal tumor is granulosa cell tumor, which composes 1% of 2% of all malignant ovarian tumors. There are two types of granulosa cell tumors an adult type that occurs mainly in postmenopausal... [Pg.730]

Several antibodies have proven to be invaluable for the diagnosis of sex cord-stromal tumors. These include... [Pg.731]

Small cell carcinoma stains more intensely for cytokeratin, and a majority of small cell carcinomas are EMA positive. h500 Most sex cord-stromal tumors are... [Pg.733]

Sex cord-stromal tumors can be either positive or negative for CK. [Pg.735]

Sex cord-stromal tumors are almost always EMA negative. Positive staining for EMA suggests an epithelial tumor, either primary or metastatic, that is mimicking a sex cord-stromal tumor. [Pg.735]

Calretinin is a more sensitive, but less specific marker for sex cord-stromal tumors than inhibin. [Pg.735]

Other markers for sex cord-stromal tumors include CD56, WEI, and SE-1. [Pg.735]

The immunophenotype of the FATWO overlaps with that of epithelial and sex cord-stromal tumors, but positive cytoplasmic staining for CD10 may help differentiate it. Lack of staining for EMA and positive staining for inhibin differentiate the FATWO from an endometrioid carcinoma variant. [Pg.744]

Zheng W, Senturk BZ, Parkash V. Inhibin immunohistochemical staining A practical approach for the surgical pathologist in the diagnoses of ovarian sex cord-stromal tumors. Adv Anat Pathol. 2003 10 27-38. [Pg.754]

Rishi M, Howard LN, Bratthauer GL, et al. Use of monoclonal antibody against human inhibin as a marker for sex cord stromal tumors of the ovary. Am J Surg Pathol. 1997 21 583-589. [Pg.754]

Matias-Guiu X, Pons C, Prat J. Mullerian inhibiting substance, alpha-inhibin, and CD99 expression in sex cord-stromal tumors and endometrioid ovarian carcinomas resembling sex cord-stro-mal tumors. Hum Pathol. 1998 29 840-845. [Pg.755]

Cao QJ, Jones JG, Li M. Expression of calretinin in human ovary, testis, and ovarian sex cord-stromal tumors. Ini J Gynecol Pathol. 2001 20 346-352. [Pg.755]

McCluggage WG, McKenna M, McBride HA. CD56 is a sensitive and diagnostically useful immunohistochemical marker of ovarian sex cord-stromal tumors. Int J Gynecol Pathol. 2007 26 322-327. [Pg.758]

Riopel MA, Perlman EJ, Seidman JD, et al. Inhibin and epithelial membrane antigen immunohistochemistry assist in the diagnosis of sex cord-stromal tumors and provide clues to the histogenesis of hypercalcemic small cell carcinomas. Int J Gynecol Pathol. 1998 17 46-53. [Pg.758]

Oliva E, Garcia-Miralles N, Vu Q, et al. CDIO expression in pure stromal and sex cord-stromal tumors of the ovary An immunohistochemical analysis of 101 cases. Int J Gynecol Pathol. 2007 26 359-367. [Pg.758]

Zhao C, Vinh TN, McManus K, et al. Identification of the most sensitive and robust immunohistochemical markers in different categories of ovarian sex cord-stromal tumors. Am J Surg Pathol. 2009 33 354-366. [Pg.758]

See other pages where Sex cord stromal tumor is mentioned: [Pg.1388]    [Pg.236]    [Pg.644]    [Pg.721]    [Pg.722]    [Pg.722]    [Pg.723]    [Pg.724]    [Pg.727]    [Pg.728]    [Pg.730]    [Pg.730]    [Pg.731]    [Pg.731]    [Pg.732]    [Pg.732]    [Pg.735]    [Pg.735]    [Pg.735]    [Pg.739]    [Pg.744]    [Pg.746]   
See also in sourсe #XX -- [ Pg.1388 ]



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