Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Sepsis fungal

Gram-positive and gram-negative bacteria, fungal species, anaerobes, and viruses cause sepsis. [Pg.1185]

The CSFs should not be used routinely for treatment of febrile neutropenia in conjunction with antimicrobial therapy.5 However, the use of CSFs in certain high-risk patients with hypotension, documented fungal infection, pneumonia, or sepsis is reasonable. A recent meta-analysis demonstrated that hospitalization and neutrophil recovery are shortened and that infection-related mortality is marginally improved.14 As with prophylactic use of these agents, cost considerations limit their use to high-risk patients. [Pg.1473]

Amphotericin B remains the drug of choice in the treatment of invasive aspergillosis, locally invasive mucormycosis, and many disseminated fungal infections occurring in immunocompromised hosts (the patient population most at risk for serious fungal infections). For example, the febrile neutropenic oncology patient with persistent fever despite empirical antibacterial therapy is best treated with amphotericin B for possible Candida spp. sepsis. [Pg.597]

A 65-year-old man with acute leukemia recently underwent induction chemotherapy and subsequently developed neutropenia and fever (with no source of fever identihed). Fever persisted despite the use of empirical antibacterial therapy, and amphotericin B has been prescribed for possible fungal sepsis. Which laboratory test is LEAST helpful in monitoring for toxicities associated with amphotericin B ... [Pg.603]

Answer Chronic disseminated candidiasis (he-patosplenic candidiasis) occurs in patients with profound neutropenia. This patient was appropriately treated for possible fungal sepsis when antibacterial therapy failed to resolve fever in the setting of neutropenia. Despite therapy, however, the patient did have disseminated candidiasis, which persisted in a subchnical state during the long period of neutrope-... [Pg.605]

Serious adverse events occur in up to 6% of patients with anti-TNF therapy. The most important adverse effect of these drugs is infection due to suppression of the ThI inflammatory response. This may lead to serious infections such as bacterial sepsis, tuberculosis, invasive fungal organisms, reactivation of hepatitis B, listeriosis, and other opportunistic infections. Reactivation of latent tuberculosis, with dissemination, has occurred. Before administering anti-TNF therapy, all patients must undergo purified protein derivative (PPD) testing prophylactic therapy for tuberculosis is warranted for patients with positive test results. More common but usually less serious infections include upper respiratory infections (sinusitis, bronchitis, and pneumonia) and cellulitis. The risk of serious infections is increased markedly in patients taking concomitant corticosteroids. [Pg.1329]

Systemic infection induced by the Trichosporon species (s. tab. 26.2) may lead to sepsis and, in the liver, to marked hepatitis-like findings, granulomas and micro-absesses. Laboratory tests revealed an increase in transaminases, alkaline phosphatase and bilirubin. Diagnosis was confirmed by liver biopsy and fungal culture. (41,42)... [Pg.508]

Leukocytosis is a normal host defense to infection and is an important adjunct to antimicrobial therapy. Unfortunately, bacterial infection is a common complication of neutropenia from cancer chemotherapy. These patients are incapable of increasing their WBCs in response to infection. In fact, susceptibility to infection in these patients is highly dependent on their WBC status. Patients with neutrophil counts of less than 500 cells/mm are at high risk for the development of bacterial or fungal infections. The absence of leukocytosis also occurs in the elderly and in severe cases of sepsis. ... [Pg.1892]

Future opportunities include rapid detection and identification of bacterial causes of sepsis and meningitis, with the ability in the latter to differentiate viral and fungal etiologies. Universal primers have been described that are conserved in all eubacteria tested and a similar situation exists for fungi and enteroviruses (B3, R6, W8). A coamplification test that combines primers for the three types of agents could prove medically useful in selecting therapy if the result can be obtained in 2 hours. [Pg.185]

Catheter site sepsis is a constant fear in these patients. The nutrient-containing infusion fluids are. of course, also excellent bacterial and fungal growth media, and risk of infection is further heightened by the presence of a foreign body, the catheter. Strict attention to aseptic-technique both in the siting of a catheter and in its maintenance will serv e to avoid many of these problems. [Pg.16]


See other pages where Sepsis fungal is mentioned: [Pg.957]    [Pg.1186]    [Pg.1469]    [Pg.47]    [Pg.53]    [Pg.57]    [Pg.172]    [Pg.417]    [Pg.2018]    [Pg.63]    [Pg.604]    [Pg.63]    [Pg.1107]    [Pg.65]    [Pg.69]    [Pg.326]    [Pg.343]    [Pg.536]    [Pg.536]    [Pg.1578]    [Pg.2133]    [Pg.2133]    [Pg.2138]    [Pg.2203]    [Pg.2259]    [Pg.2607]    [Pg.2607]    [Pg.187]    [Pg.454]    [Pg.445]    [Pg.63]    [Pg.186]    [Pg.722]    [Pg.136]    [Pg.41]   
See also in sourсe #XX -- [ Pg.1186 ]

See also in sourсe #XX -- [ Pg.2133 ]




SEARCH



© 2024 chempedia.info