Search parameters

Patent classification codes are another subject-search parameter available in most patent databases. IPC codes are usually present and U.S. codes exist in a number of files in the case of Japan Patent Information Organization (JAPIO), Japanese codes too are available. It is possible to mimic a hand search by limiting operations to references falling within one class or group of classes. Although such strategies can in some instances be justified, it is usually wiser to treat class codes as just one of the various subject parameters that make up a search strategy. 

Identify suitable reactants most similar to the corresponding virtual reactants obtained from step 1 in order to focus on the most relevant sub-regions. But the disconnection does not necessarily result in bona fide known and available starting materials, after just step 1. Consider as an example a two-component reaction which in the PGVL has M suitable bona fide reactants for the first reaction component and N suitable bona fide reactants for the second reaction component. Two similarity searches are used in the step to select m (out of M) and n (out of N) reactants based on two virtual reactants as seeds, which arose from the exact disconnection of the query molecule. In most cases, M and N are 103, and m and n are 102. Here extra search parameters need to be specified and/or optimized for each reaction component. 

For instance, if a significance level of 95% is to be reached, at least 19 randomization runs need to be performed. If one cannot reach an acceptable level of significance, a new dataset and different searching parameters must be used. 

A convenient way to find the trajectory satisfying the boundary condition is to take t as a complex search parameter. In order to obtain the quanmm probability as a function of Q2, we should change the end coordinate Q2 in the real line with fixed 2 real, then the search parameter t will trace a ID set on the complex plane—that is, ID curves. According to Shudo and Ikeda [15], we call such a set on the complex initial time plane t the -set, which is defined by [22]... 

The Estimates, Derivatives and Search parameters can be changed to optimize the solution process. The Search parameter specifies which gradient search method to use the Newton method requires more memory but fewer iterations, the Conjugate method requires less memory but more iterations. The Derivatives parameter specifies how the gradients for the search are calculated the Central derivatives method requires more calculations but may be helpful if the Solver reports that it is unable to find a solution. The Estimates parameter determines the method by which new estimates of the coefficients are obtained from previous values the Quadratic method may improve results if the system is highly nonlinear. 

This BLAST Quickstart chapter illustrates the use of the principal BLAST programs to solve problems that arise in the analysis of protein and nucleotide sequences. Each section provides a succinct description of a protocol with two problems that serve as practical examples. Relevant theory is given when it affects the selection of a search strategy or search parameter, however, the emphasis is on the procedure itself. The sections follow closely the structure of the BLAST QuickStart Mini-Course found at www.ncbi.nlm.nih.gov/Class/minicourses. The BLAST QuickStart is one of 10 2-h format Mini-Courses offered by NCBI on campus at the National Institutes of Health and at locations around the country to over 4000 students a year. The courses use a paired problems approach in which the first of two similar problems or problem sets is solved by the instructor during the first hour on a computer linked to a projection system, while the students watch in the second hour, the students tackle the second problem, or set of problems at their... 

Two factors contribute to the difficulty of searching 3D databases. First is the difficulty in specifying the search parameters. How are similar shapes defined Second, although the conformation stored in the database may be the most probable conformation (either the crystal structure or an energy minimum), in some cases a higher energy conformation is the biologically active one. Therefore, conformational flexibility should be included in the search process.Different methods have been developed to carry out searches in three dimensions. Detailed introductions to the problems and methods of 3D... 

Although some efforts have been made to include compound potency as a search parameter ]32], LEVS methods generally treat biological activity in a qualitative maimer, that is, reference compounds are not distinguished by potency differences. 

Database search parameters for the TOF/TOF data using the Mascot search engine Homo sapiens for taxonomy, NCBIr for database, no enzyme, no modifications, mass tolerance of the precursor ion at 0.2 kDa and the fragment ions at ... 

The form of Lq in Equation 19.9 depends on the experimental conditions used, the form of the scatterers, and the searched parameters. For instance, it is proportional... 

The Peak Picking command helps you to identify peaks in your spectra. The command offers high flexibility by allowing you to adjust and fine tune the search parameters. 

On the Search Parameter page (Fig. 11.27) you define the desired search parameters ... 

Spectrum Search Search Parameters Excluded Regions Select Libraries ... 

Figure 11.27. The Spectrum Search dialog box Search Parameters page.

The Web Watch directory, an online search engine of plastics industry-relevant websites, allows users to select from approximately sixty descriptions of companies or organizations (such as associations, blow molders, extrusion machinery suppliers, compounders, consultants, and so on). When searching for a certain type of processor, users can filter further by choosing the type of end market served (such as injection molders and medical). The search-results pages provide links directly to the sites that match your search parameters. Inclusion in and use of the Web Watch directory is free. 

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