Screening single-cell study

PLD has also been utilized to produce bilayer electrolytes. In one study, aNiO-YSZ (anode support, tape cast)/NiO-SDC (AFL, screen-printed)/ScSZ-SDC (electrolyte bilayer, PLD)/SSC (cathode, screen-printed) cell showed excellent performance (0.5 and 0.9 W/cm2 at 550 and 600°C, respectively), with an OCV of 1.04 V at 600°C, indicating that the PLD technique was successful in depositing a sufficiently dense ScSZ electronic blocking layer to suppress electronic conduction normally observed across single-layer SDC electrolytes, and which typically result in lower OCV values (0.87 V, 600°C) [46, 127],... 

The latest development in bioorganic chemistry concerns the study of chemical processes within a cell. The incorporation of cells in a microreactor enables the investigation of the effect of all kinds of molecules on the behavior and the metabolic processes of a single cell. Although still in its infancy, this line of research holds much promise for more effective pharmaceutical screening processes and biotechnology applications. 

The lesson learned from these case studies was that in vitro models can be used as screening tools when investigating direct injury to a relevant single cell type, but traditiontd two-dimensional (2D) cell culture models often bear little physical, molecular, or physiological similarity to the pancreas in vivo. This highhghts a need to continue efforts to define more complex multicell systems, such as organotypic and ex vivo models, for assessment of drug candidate-induced pancreatic toxicity. 

Fluorescence lifetime imaging Study of single cells, bulk tissue, dynamics of intercellular and intracellular processes, bimolecular interactions Noninvasive technique, highly sensitive Microanalysis of sample arrays, high-throughput screening... 

The activity and performance of fuel cell electrocatalysts need to be evaluated in terms of electrochemieal parameters, including current density and electrode potential. Electrochemieal sereening methods have been identified as ideal direct approaches for combinatorial studies of fuel cell catalysts. Two types of electrochemical measurement systems have been developed for combinatorial screening of fuel cell catalysts the array half-cell system and the array single-cell system. 

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