Salviae miltiorrhizae Danshen

In China, the root of Salvia miltiorrhiza (danshen) has been used traditionally for the treatment of coronary diseases. [Pg.1986]

Lam FF, Yeung JH, Chan KM, Or PM (2008) Dihydrotanshinone, a Upophilic component of Salvia miltiorrhiza (danshen), relaxes rat coronary artery by inhibition of calcium chatmels. J Ethnopharmacol 119 318... [Pg.3577]

NMR, UV and IR spectroscopies are routinely used for the characterization of the majority of reviewed systems and the reader is referred to the individual references for this information. The special cases of structure elucidation of a secondary metabolite of the Chinese drug Danshen Salvia miltiorrhiza Bunge) by... [Pg.69]

Warfarin Danshen (Salvia miltiorrhiza) Increased INR, prolonged PT/PTT Danshen decreases elimination of warfarin... [Pg.39]

Although not commonly used in the U.S., danshen (the root of Salvia miltiorrhiza), also known as tan seng, is a very popular herb recommended in Chinese medicine for various cardiovascular diseases. The pharmacological effects of danshen have been described primarily in vitro and also in animals and include the following ... [Pg.45]

Chan lY. Interaction between warfarin and danshen Salvia miltiorrhiza). Ann Pharmacother 2001 35(4) 501. ... [Pg.1988]

Chan K, Lo AC, Yeung JH, Woo KS. The effects of Danshen Salvia miltiorrhiza) on warfarin pharmacodynamics and pharmacokinetics of warfarin enantiomers in rats. J Pharm Pharmacol 1995 47(5) 402-6. [Pg.1988]

Tanshinones. Tanshinones extracted from Chinese herb Danshen Salvia Miltiorrhiza Bunge) were traditionally used as antiinflammation and cerebrovascular drugs due to their antioxidation and antiacetylcholinesterase effects. Tanshinones protect neuronal cells. Tanshinone I (TS1) and tanshinone IIA (TS2), the two major components in the Danshen herb, inhibit the aggregation and toxicity of Ap1 42 Both TS1 and TS2 exhibit different inhibitory abilities to prevent unseeded amyloid fibril formation and to disaggregate preformed amyloid fibrils, in which TS1 shows better inhibitory potency than TS2 [235]. [Pg.405]

Coumarins and related drugs + Herbal medicines Danshen (Salvia miltiorrhiza)... [Pg.415]

Methyl salicylate, in the form of gels, oil, or ointment applied to the skin, has been found to increase the effects of warfarin. Bleeding and bruising and/or raised INRs have been seen with both high " and low doses of methyl salicylate. One report described the possible additive effects of methyl salicylate oil (Kwan Loong Medicated Oil) and a decoction of Danshen (the root of Salvia miltiorrhiza) on the response to warfarin (see also Coumarins and related drugs + Herbal medicines Danshen (Salvia miltiorrhizay, p.415). A raised prothrombin time has also been reported with topical trolamine salicylate. ... [Pg.457]

Lam, EE, J.H. Yeung, and J.H. Cheung. 2005. Mechanisms of the dilator action of danshen (Salvia miltiorrhiza) on rat isolated femoral artery. /. Cardiaoasc. Pharmacol. 46(3) 361-368. [Pg.770]

Chang HM, Cheng KP, Choang TF (1990) Structure elucidation and total synthesis of new tanshinones isolated from Salvia miltiorrhiza Bunge (Danshen). J Org Chem 55 3537... [Pg.3575]

Root and rhizome of Salvia miltiorrhiza Bge. (Family Labiatae or Lamiaceae), a hairy perennial herb, 30-80 cm high native to China and widely distributed there. Root (with rhizome) is dug up in spring and autumn, rid of rootlets, sand and dirt, and sun dried. Other species also used as source of danshen include Salvia przewalskii Maxim, (gansu danshen), S. przewalskii Maxim, var. mandarinorum (Diels) Stib., S. bowleyana Dunn (southern danshen) and S. yunnanensis C. H. Wright they all have similar chemistry. [Pg.680]

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