Salvia miltiorrhiza

The use of ultrasonic (US) radiation (typical range 20 to 850 kHz) to accelerate Diels-Alder reactions is undergoing continuous expansion. There is a parallelism between the ultrasonic and high pressure-assisted reactions. Ultrasonic radiations induce cavitation, that is, the formation and the collapse of microbubbles inside the liquid phase which is accompanied by the local generation of high temperature and high pressure [29]. Snyder and coworkers [30] published the first ultrasound-assisted Diels-Alder reactions that involved the cycloadditions of o-quinone 37 with appropriate dienes 38 to synthesize abietanoid diterpenes A-C (Scheme 4.7) isolated from the traditional Chinese medicine, Dan Shen, prepared from the roots of Salvia miltiorrhiza Bunge. [Pg.154]

Asymmetric synthesis of Salvia miltiorrhiza abietanoid o-quinones methyl tanshino-nate, tanshinone IIB, tanshindiol B and 3-hydroxytanshinone [30c]... [Pg.195]

Isolation of cryptotanshinone, an active quinoid diterpene formed in callus of Salvia miltiorrhiza BUNGE... [Pg.224]

Cytotoxic diterpenes Salvia miltiorrhiza SiOj RP18 Hx - AcOEt MeOH - H2O — Isolation 51 i— L> -< 0)... [Pg.262]

Tanshinones isolated from the dried root of Salvia miltiorrhiza Bunge abrogated the survival of P388 lymphocytic leukemia cells cultured in vitro. Tanshinone I and tanshinone IIA showed 86.76 and 56.05% cell inhibition, respectively, at a dose of 25 pig/mL) (54). Dihydrotanshinone I and cryptotanshinone were relatively cytotoxic (55). Dihydrotan-shinone I induces cell growth anest during the S phase and, subsequently, apoptosis. [Pg.205]

Liu J, Shen HM, Ong CN. Salvia miltiorrhiza inhibits cell growth and induces apoptosis in human hepatoma HepG2 cells. Cancer Lett 2000 153 85-93. [Pg.226]

Yang LJ, Jeng CJ, Kung HN, et al. Tanshinone IIA isolated from Salvia miltiorrhiza elicits the cell death of human endothelial cells. J Biomed Sci 2005 12 347-361. [Pg.226]

Mosaddik MA. In vitro cytotoxicity of tanshinones isolated from Salvia miltiorrhiza Bunge against P388 lymphocytic leukemia cells. Phytomedicine 2003 10 682-685. [Pg.226]

Zhang, H., and Cheng, Y. (2006). Solid-phase extraction and liquid chromatography-electrospray mass spectrometric analysis of saponins in Chinese patent medicine of formulated Salvia miltiorrhizae and Panax notoginseng. J. Pharm. Biomed. Anal. 40,429 32. [Pg.100]

Danshenol A (57), an abietane-type diterpenoid isolated from the dried roots and rhizomes of Salvia miltiorrhiza Bunge (family Labiatae),... [Pg.539]

Cryptotanshinone (Fig. 4), a diterpene quinone, is produced in root tissues of Salvia miltiorrhiza Bunge plants. Of remarkable anti-inflammatory effect, a maximal yield of 4.6 0.1 mg of cryptotanshinone/g dw was detected in a 60-day-old callus of S. miltiorrhiza cultured in 0.2-mg/L N -benzyladenine-supplemented Murashige and Skoog medium. ... [Pg.640]

Wu CT, Vanisree M, Satish MN, Chen CL, Yang TF, Tsay HS. (2003) Isolation and quantitative analysis of cryptotanshinone, an active quinoid diterpene formed in the callus of Salvia miltiorrhiza Bunge. Biol Pharm Bull 26 845-848. [Pg.651]

NMR, UV and IR spectroscopies are routinely used for the characterization of the majority of reviewed systems and the reader is referred to the individual references for this information. The special cases of structure elucidation of a secondary metabolite of the Chinese drug Danshen Salvia miltiorrhiza Bunge) by... [Pg.69]

Qiao X, Zhang Z, Ping Z (2007) Hydrophilic modification of ultrafiltration membranes and their application in Salvia miltiorrhiza decoction. Separ Purif Technol 56 265-269... [Pg.124]

Wang AM, Sha SH, Lesniak W, Schacht J. Tanshinone (Salviae miltiorrhizae extract) preparations attenuate aminoglycosides-induced free radical formation in vitro and ototoxicity in vivo. Antimicrob Agents Chemother 2003 47 1836-1841. [Pg.143]

Wu, Y. J., C. Y. Hong, S. J. Lin, P. Wu, and M. S. Shiao. 1998. Increase of vitamin E content in LDL and reduction of atherosclerosis in cholesterol-fed rabbits by a water-soluble antioxidant-rich fraction of Salvia miltiorrhiza. Arterioscler. Thromb. Vase. Biol. 18 481-486. [Pg.331]

Kasimu, R., P. Basnet, Y. Tezuka, S. Kadota, and T. Namba. 1997. Danshenols A and B, new aldose reductase inhibitors from the root of Salvia miltiorrhiza Bunge. Chem. Pharm. Bull. 45 564-566. [Pg.336]

Scrophulariae radix), Dan Shen (Salviae miltiorrhizae radix), Xi Xin (Asari herba), ... [Pg.7]

D Lu (Veratri nigri radix et rhizoma) is incompatible with Ren Shen (Ginseng radix), Sha Shen - Bei Sha Shen (Glehniae radix)/Nan Sha Shen (Adenophorae radix), Ku Shen (Sophorae flavescentis radix), Xuan Shen (Scrophulariae radix), Dan Shen (Salviae miltiorrhizae radix), Xi Xin (Asari herba), ... [Pg.28]

Burning pain in the stomach due to Stomach-heat and Liver-heat add Dan Shen (Salviae miltiorrhizae radix), Huang Lian (Coptidis rhizoma) and Mei Gui Hua (Rosae flos) to reduce heat and regulate the Qi. [Pg.229]

Wu Ling Zhi (Trogopterori faeces), Ze Lan (1 ycopi herba), Yue Ji Hua (Rosae chinensis flos), Dan Shen (Salviae miltiorrhizae radix), Yu Jin (Curcumae radix) and Yi Mu Cao (Leonuri herba)... [Pg.275]

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