Salicylic acid genes

Staurosporine, a kinase inhibitor, also suppressed PAL transcription and enzymatic activation, which indicates that the phosphorylation of still unknown (transcription) factors happened in response to stimulation by pectic fragments. However, another staurosporine-insensitive but salicylic acid responding pathway led to the transcription of pathogenesis related (PR) genes [26]. 

Transvalencin Z (245a) from Nocardia transvalensis could be a precursor or side product of mycobactin biosynthesis, possibly acquired from a vagabonding gene. It comprises the left part of the serine/salicylic acid based molecules (Table 5 R" = = H) and ends with A/ -formyl-Lys (R = H, no iV-hydroxy group). The... 

Mercado-Bianco J, van der Drift KMGM, Olsson PE, Thomas-Oates JE, van Loon LC, Bakker PAHM (2001) Analysis of the pmsCEAB Gene Cluster Involved in Biosynthesis of Salicylic Acid and the Siderophore Pseudomonine in the Biocontrol Strain Pseudomonas fluorescens WCS374. J Bacteriol 183 1909... 

Salicylic acid is an inducer of antifungal proteins (Figure 4.38) and is proposed to activate the expression of SAR genes in the plant.21... 

The product of step o is known as isochoris-mate.55 56 Isochorismate gives rise to a variety of products including vitamin K, salicylic acid,56a the iron chelator enterobactin (Fig. 16-1), and other siderophores. These are formed in E. coli via 2,3-dihy-droxybenzoate as indicated in Fig. 25-2.57-59a The genes (ent) for the requisite enzymes are clustered at 14 min on the E. coli chromosome map (Fig. 26-4). 

A metabolic engineering approach has now provided direct evidence for the role of salicylic acid in systemic acquired resistance. Transgenic tobacco plants were produced expressing the "nah G" gene from Pseudomonas putida, which encodes a salicylate hydroxylase that converts salicylic acid... 

In summary, we have identified salicylic acid as a candidate for the endogenous signal that mediates SAR. The addition of this compound to leaves induces the biological response and also induces the synthesis of marker genes that have been correlated with the onset of SAR. However, it has not been possible to induce the phenomenon systematically by the addition of exogenous SA and this is apparently due either to the rapid metabolism of the compound or to its inability to gain access to the vascular system. 

J Beck, S Ripka, A Siegner, E Schiltz, E Schweizer. The multifunctional 6-methyl-salicylic acid synthase gene of Penicillium patuhmv. its gene structure relative to that of other polyketide synthases. Eur J Biochem 192 487-498, 1990. 

Renault, A.S., Deloire, A., Bierne, J. (1996). Pathogenesis-related proteins in grapevines induced by salicylic acid and Botrytis cinerea. Vitis, 35, 49-52 Robert, N., Roche, K., Lebeau, Y., Breda, C., Boulay, M., Esnault, R., Buflfard, D. (2002). Expression of grapevine chitinase genes in berries and leaves infected by fungal or bacterial pathogens. Plant Sci., 162, 389-400... 

Fraissinet-Tachet, L., Baltz, R., Ghong, J., Kauffmann, S., Fritig, B. and Saindrenan, P (1998) Two tobacco genes induced by infection, elicitor and salicylic acid encode glucosyltransferases acting on phenylpropanoids and benzoic acid derivatives, including salicylic acid. FEBS Lett., 437, 319-23. 

Degradation products of LOOHs are able to initiate the production of the ethylene, kinases and G-proteins required to induce an oxidative burst. These events are apparently followed by activation of the genes which encode the generation of jasmonic acid and of salicylic acid. These are in turn able to induce the production of enzymes of the phenylpropanoid pathway [149,150], and enzymes which initiate the biosynthesis of terpenes (e.g. 3-hydroxy-3-methylglutaryl coenzyme A reductase [145,151-153]) and lignins. 

Kim SH, Choi JH, Park HS et al (2005) Association of thromboxane A receptor gene polymorphism with the phenotype of acetyl salicylic acid-intolerant asthma. Clin Exp Allergy 35 585-590... 

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