Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Ring system derivatives, 2-functionalized

Hernadez Daranas et al. have explored the conformations of five-membered ring systems (derivatives of furan), by NMR spectroscopy, molecular dynamic methods (MD) and DFT calculation of J(H,H), J(C.H) and V(C,H) couplings. Couplings were calculated as the functions of pseudorotational phase angles, and compared with the experimental ones. Such an approach allowed identifying ring conformations. [Pg.176]

The use of multilegged molecules for clathrate formation is not limited to a single ring bearing just six appendages. A fully substituted naphthalene carries 8 groups, anthracene 10, and triphenylene and coronene each have 12 substituents. MacNicol has demonstrated that appropriate derivatives of all these ring systems can function as successful hosts and the representative... [Pg.2367]

Thiophene [110-02-1] and a number of its derivatives are significant in fine chemical industries as intermediates to many products for pharmaceutical, agrochemical, dyestuffs, and electronic appHcations. This article concentrates on the industrial, commercial, and economic aspects of the production and apphcations of thiophene and thiophene derivatives and details the main synthetic schemes to the parent ring system and simple alkyl and aryl derivatives. Functionalization of the ring and the synthesis of some functional derivatives that result, not from the parent ring system, but by direct ring cyclization reactions are also considered. Many good reviews on the chemistry of thiophene and thiophene derivatives are available (1 7). [Pg.17]

Fused ring systems containing a pyrazole unit can be prepared either from the heterocyclic moiety by formation of a pyrazole ring or from the reaction between a pyrazole derivative and a suitably functionalized reagent. The ring systems thus obtained are discussed in detail in other chapters (Chapters 4.05, 4.35, 4.36) but it is of interest to discuss here those methods which start from a pyrazole derivative as the reactions involved can be considered as examples of the reactivity of pyrazoles. The most widely studied fused ring systems are the [5.6] systems and the examples described in this section will be chosen from this group and, occasionally, from [5.5] and [5.7] systems. [Pg.271]

An intramolecular variant of the Baylis-Hillman reaction is also possible, and may be used for the construction of functionalized ring systems, e.g. a cyclopen-tene derivative such as 12. However, good yields have been achieved in only a few cases ... [Pg.30]

The photochemical reaction of azide-functionalized tetrazole derivatives such as 38 leads to the formation of the 5-5 bicyclic ring system 40 (Scheme 5) in very moderate yields <1999JHC863>. This reaction is believed to proceed via the singlet nitrene intermediate 39. Attack at the aromatic substituent in ortho position leads to product 40 <1974JOG2546> by subsequent cyclization. This intermediate is deprotonated during the workup conditions to the mesoionic tricyclic derivative 41. [Pg.356]

The hydrolysis product 51 can alternatively be accessed directly from the reaction of the thiol derivative 48 with chloro acetamide. Other electrophiles for the reaction with the thiol derivative were also described which lead to functionalized tetrazole or 5-6 fused bicyclic ring systems. [Pg.358]

Also, the intramolecular [3+2] cycloaddition approach can be used to generate several tricyclic ring systems 66-68 when the azide and the cyanamide functionalities are bonded to a carbocyclic ring <20010L4091> (Scheme 14). The relative stereochemistry of the starting materials is preserved in the products. While the yield of the m-fused 5-5-6 tricyclic ring system 66 is very high, the yield of the trans-fuseA products 67 and 68 is considerably lower as expected based on the unfavorable conformation for the cycloaddition process. The even lower yield for the tosylated and therefore activated derivative 68 was rationalized by its decreased thermal stability. [Pg.359]

The chiral distinction capability of cinchonan carbamate CSPs for underivatized amino acids has not been fully elucidated yet, in contrast to the large embodiment of A-acylated and A-arylated amino acid derivatives vide infra). However, it seems that chiral amino acids can be successfully resolved into enantiomers if the amino acid side chain R residue) contains a functionality that represents a strongly interactive binding site with the selector such as an extended aromatic ring system like in thyroxin (T4). [Pg.66]


See other pages where Ring system derivatives, 2-functionalized is mentioned: [Pg.148]    [Pg.294]    [Pg.137]    [Pg.139]    [Pg.316]    [Pg.199]    [Pg.448]    [Pg.74]    [Pg.83]    [Pg.114]    [Pg.159]    [Pg.425]    [Pg.86]    [Pg.97]    [Pg.342]    [Pg.249]    [Pg.132]    [Pg.51]    [Pg.99]    [Pg.104]    [Pg.242]    [Pg.64]    [Pg.530]    [Pg.4]    [Pg.383]    [Pg.708]    [Pg.10]    [Pg.73]    [Pg.360]    [Pg.485]    [Pg.905]    [Pg.969]    [Pg.988]    [Pg.992]    [Pg.1]    [Pg.706]    [Pg.429]    [Pg.5]    [Pg.11]    [Pg.113]    [Pg.121]    [Pg.178]   
See also in sourсe #XX -- [ Pg.183 ]




SEARCH



Derivative Systems

Derivative function

Function derived

Functional systems

© 2024 chempedia.info