Binding-site interactions

In addition to variations in toxin structure, the nature of the binding site and the medium in which binding occurs both influence the observed behavior of the toxins and can be systematically varied to study the toxin/binding site interaction. These factors will not be discussed at length here, but should be remembered as complications in comparing different data sets. 

Experimental Methods for Characterizing Binding Site Interactions... 

Computational analysis of binding site interactions is achieved by calculating the relative binding free energy (AAGbind) for a ligand L with an... 

Figure 2. Binding site interactions of Human FBPase (C4) with AMP.

In these aggregation phenomena, the formation of intermacromolecular complexes is attributed to the fact that macromolecules with complementary binding sites interact with each other almost stoichiometrically in solution due to certain secondary binding forces. In this review, the formation of complementary complexes in synthetic macromolecular systems is mainly discussed. 

Molecular imprinting with covalent or stoichiometric non-covalent interactions 81 4.4. THE ROLE OF THE BINDING-SITE INTERACTIONS... 

BINDING SITE INTERACTIONS IN MOLECULARLY IMPRINTED POLYMERS... 

Homotropic this is where the sites are identical, and each sites is allosteric to the others. This is like the cooperative interactions seen in oxygen binding by haemoglobin - four (essentially) identical oxygen binding sites interacting with each other allosterically. 

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