Rho D Immune Globulin

In addition to its antiviral actions, interferon has an antiproliferative effect and modifies the functions of macrophages and natural killer cells. Thymosin, a protein synthesized by the epithelioid component of the thymus, may be potentially valuable in patients with DiGeorge s syndrome or other T cell deficiency states. Levamisole augments T cell-mediated immunity and may be of value in the immunodeficiency associated with Hodgkin s disease. [Pg.498]

The regulation of immune parameters by P. major leaf extract (plantain) may be clinically relevant in numerous diseases including chronic viral infections, tuberculosis, AIDS, and cancer. [Pg.498]

Rho(D) immune globulin is one of the most specific and effective immunosuppressive treatments available. These IgG antibodies have high Rh(D)-specific titers. Administration of Rho(D) immune globulin prevents the response that develops in Rh mothers who were pregnant with an Rh+ fetus and consequently have become sensitized to the D antigen on fetal erythrocytes of the infant. In these Rh mothers, the antibody titers against Rh+ cells will continue to rise after each subsequent [Pg.101]

The monoclonal antibodies used as immunosuppressive agents in tissue transplantation include muromonoab-CD3, daclizumab and basiliximab. Muromonoab-CD3 binds to a specific site on CD3 receptors and interferes with the ability of the TCR to bind the antigen and also inhibits CD3 receptor-dependent signal transduction mechanisms, all of which result in immune suppression. Both daclizumab and basiliximab are monoclonal antibodies directed against IL-2 receptors and consequently inhibit IL-2-dependent responses after tissue transplantation, resulting in immune suppression. The monoclonal antibodies used as immunosuppressive agents are described in detail in Chapter 5. [Pg.102]

A) Yes. The mother should receive Rho(D) immune globulin to prevent hemolytic anemia in future neonates. [Pg.663]

Rho(D) immune globulin (hnman) [FDA] Rho(D) immune globulin [USAN]... [Pg.512]

Hemolytic disease of the newborn Rho(D) immune globulin Excellent... [Pg.1190]

The usual dose of Rho(D) immune globulin is 2 mL intramuscularly, containing approximately 300 meg anti-Rh0(D) IgG. Adverse reactions are infrequent and consist of local discomfort at the injection site or, rarely, a slight temperature elevation. Hyperimmune Immunoglobulins... [Pg.1196]

Rho D immune globulin WinRho SDF (Nabi) Immune thrombocytopenic purpurea... [Pg.276]

Rho(D) immune globulin BAY-RHO-D WINRHO SDF MICRHOGAM RHOGAM Others... [Pg.922]

Therapeutic Use Rho(D) immune globulin is indicated whenever fetal red blood cells are known or suspected to have entered the circulation of an Rh-negative mother unless the fetus is known also to be Rh-negative. The drug is given intramuscularly. The tj of circulating immunoglobulin is -21-29 days. [Pg.923]

Rho (D) immune globulin (RhoGAM) is administered to a mother who has Rh-negative blood and is pregnant with a Rh-positive fetus to prevent the development of maternal antibodies to the fetus s blood. Corticosteroids are not given for this reason. [Pg.191]

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