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Respiratory depressant drugs

Murphy, D.J., Joran, M.E., and Grando, J.C., A non-invasive method for distinguishing central from peripheral nervous system effects of respiratory depressant drugs in conscious rats, General Pharmacol., 26, 569-575,1995. [Pg.284]

Increased respiratory depression can occur if other respiratory depressant drugs, for example hypnotics, sedatives, or alcohol, are taken concurrently. Muscle relaxants and antihistamines with sedative properties have a similar effect. [Pg.2635]

Fatigue, drowsiness, as adjunct in analgesic formulation, respiratory depression Drug-induced postanesthesia, drug-induced respiratory depression, acute respiratory insufficiency superimposed on COPD Narcolepsy... [Pg.248]

Hypoventilation is the opposite of hyperventilation and is eharaeterized by an inability to exerete CO9 rapidly enough to meet physioiogieai needs. Hypoventilation ean be eaused by nar-eoties, sedatives, anestheties, and depressant drugs diseases of the lung also lead to hypoventilation. Hypoventilation results in respiratory acidosis, as C09(g) aeeumulates, giving rise to H9CO3, whieh dissoeiates to form H and HCOa. ... [Pg.54]

When kaolin or aluminum is administered widi die lincosamides, die absorption of the lincosamide is decreased. When the lincosamides are administered with the neuromuscular blocking drag (drag diat are used as adjuncts to anesthetic drag diat cause paralysis of the respiratory system) die action of die neuromuscular blocking drug is enhanced, possibly leading to severe and profound respiratory depression. [Pg.87]

Narcotic analgesics can produce serious or potentially fatal respiratory depression if given too frequently or in an excessive dose. Respiratory depression may occur in patients receiving a normal dose if the patient is vulnerable (ie, in weakened state or debilitated state). Elderly, cachectic, or debilitated patients may have a reduced initial dose until die response of the drug is known. If the respiratory rate is 10/min or below, the nurse must monitor die patient at frequent intervals and notify the primary health care provider immediately. [Pg.173]

The risk of respiratory depression is a concern for many nurses administering a narcotic and may cause some nurses to hesitate to administer the drug. However, respiratory depression rarely occurs in patients using a narcotic for pain. In fact, these patients usually develop tolerance to the respiratory depressant effects of the drug very quickly. Naloxone (see Chap. 20) can be administered to reverse the narcotic effects if absolutely necessary. [Pg.174]

This drug is used for complete or partial reversal of narcotic depression, including respiratory depression. Narcotic depression may be due to intentional or accidental overdose (self-administration by an individual), accidental overdose by medical personnel, and drug idiosyncrasy Naloxone also may be used for diagnosis of a suspected acute opioid overdosage. [Pg.180]

When naloxone is used to reverse respiratory depression and the resulting somnolence, the drug is given stow IV push until the respiratory rate begins to increase and somnolence abates Giving a rapid bolus wilt cause withdrawal and return of intense pain. [Pg.182]

All barbiturates have essentially die same mode of action. Depending on the dose given, tiiese drags are capable of producing central nervous system (CNS) depression and mood alteration ranging from mild excitation to mild sedation, hypnosis (sleep), and deep coma These drugs also are respiratory depressants the degree of depression... [Pg.237]

MONITORING AND MANAGING RESPIRATORY DEPRESSION These drugs depress the CNS and can cause respiratory depression. The nurse carefully assesses respiratory function (rate, depth, and quality) before administering a sedative, Vs, to 1 hour after administering the drug, and frequently thereafter. Toxic reaction of the barbiturates can cause severe respiratory depression, hypoventilation, and circulatory collapse. [Pg.243]

The onset of symptoms of barbiturate toxicity may not occur until several hours after the drug is administered. Symptoms of acute toxicity include CNSand respiratory depression, constriction or paralytic dilation of the pupils tachycardia, hypotension, lowered body temperature, oliguria, circulatory collapse, and coma. The nurse should report any symptoms of toxicity to the primary health care provider immediately. [Pg.243]

Doxapram is used to treat drug-induced respiratory depression and to temporarily treat respiratory depression in patients with chronic pulmonary disease This drug also may be used during the postanesthesia period when respiratory depression is caused by anesthesia It also is used to stimulate deep breathingin patients after anesthesia... [Pg.247]

ANALEPTICS. When a CNS stimulant is prescribed for respiratory depression, initial patient assessments will include the blood pressure, pulse, and respiratory rate. It is important to note the depth of the respirations and any pattern to the respiratory rate, such as shallow respirations or alternating deep and shallow respirations. The nurse reviews recent laboratory tests (if any), such as arterial blood gas studies. Before administering the drug, the nurse ensures that the patient has a patent airway. Oxygen is usually administered before, during, and after drug administration. [Pg.250]

Respiratory depression can be a serious event requiring administration of a respiratory stimulant. When an analeptic is administered, the nurse notes and records the rate, depth, and character of the respirations before the drug is given to provide a database for evaluation of the effectiveness of drug therapy. Oxygen is usually ordered for before and after administration of a respiratory stimulant. After administration, the nurse monitors respirations closely and records the effects of therapy. [Pg.250]

Although rare, benzodiazepine toxicity may occur from an overdose of the drug. Benzodiazepine toxicity causes sedation, respiratory depression, and coma. Flumazenil (Romazicon) is an antidote (antagonist) for benzodiazepine toxicity and acts to reverse die sedation, respiratory depression, and coma within 6 to 10 minutes after intravenous administration. The dosage is individualized based on the patient s response, widi most patients responding to doses of 0.6 to 1 mg. However, die drug s action is short, and additional doses may be needed. Adverse reactions of flumazenil include agitation, confusion, seizures, and in some cases, symptoms of benzodiazepine withdrawal. Adverse reactions of flumazenil related to the symptoms of benzodiazepine withdrawal are relieved by die administration of die benzodiazepine. [Pg.279]

Use of codeine may result in respiratory depression, euphoria, light-headedness, sedation, nausea, vomiting, and hypersensitivity reactions. The more common adverse reactions associated with the antitussives are listed in the Summary Drug Table Antitussive, Mucolytic, and Expectorant Drugs. When used as directed, nonprescription cough medicines containing two or more ingredients have few adverse reactions. However, those that contain an antihistamine may cause drowsiness. [Pg.352]

EMETICS After file administration of an emetic, file nurse closely observes file patient for signs of shock, respiratory depression, or other signs and symptoms that may be part of file clinical picture of file specific poison or drug that was accidentally or purposely taken. [Pg.482]

Finally, there is little or no clinical evidence that morphine causes psychological dependence or drug-seeking behaviour, tolerance or problematic respiratory depression in patients. These events simply do not occur when opioids are used to control pain. The reason is likely to be that the actions of morphine and the context of its use in a person in pain are neurobiologically quite different from the effects of opioids in street use. These actions of opioids are described in more detail in Chapter 23. [Pg.259]

Myxedema coma is seen in advanced hypothyroidism. These patients develop CNS depression, respiratory depression, cardiovascular instability, and fluid and electrolyte disturbances. Myxedema coma often is triggered by an underlying acute medical condition such as infection, stroke, trauma, or administration of CNS depressant drugs. [Pg.672]


See other pages where Respiratory depressant drugs is mentioned: [Pg.363]    [Pg.177]    [Pg.147]    [Pg.220]    [Pg.999]    [Pg.346]    [Pg.363]    [Pg.177]    [Pg.147]    [Pg.220]    [Pg.999]    [Pg.346]    [Pg.384]    [Pg.78]    [Pg.535]    [Pg.906]    [Pg.8]    [Pg.171]    [Pg.174]    [Pg.180]    [Pg.238]    [Pg.248]    [Pg.377]    [Pg.473]    [Pg.641]    [Pg.63]    [Pg.250]    [Pg.140]    [Pg.470]    [Pg.532]    [Pg.537]    [Pg.544]    [Pg.581]   
See also in sourсe #XX -- [ Pg.147 ]




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