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Reproductive development

Many pesticides cause endocrine disruption in vertebrate and invertebrate species at concentrations that are not overtly metabolically toxic. The insect growth inhibitor diflubenzuron can affect the reproduction, development and behaviour of estuarine crustaceans at concentrations of just lOmgP (reviewed... [Pg.55]

There is some evidence from a number of animal species that phytoestrogen consumption can interfere with reproductive development and function. ... [Pg.105]

Westgate, M.E. Boyer, J.S. (1985f>). Carbohydrate reserves and reproductive development at low leaf water potentials in maize. Crop Science, 25, 762-9. [Pg.93]

Cooper, R.L. and Kavlock, R.J. (1997). Endocrine disrupters and reproductive development A weight-of-evidence overview. Journal of Endocrinology 152, 159-166. [Pg.343]

Gomot, A. 1998. Toxic effects of cadmium on reproduction, development, and hatching in the freshwater snail Lymnaea stagnalis for water quality monitoring. Ecotoxicol. Environ. Safety 41 288-297. [Pg.72]

Gray, L. E., et al. (1997b). In utero exposure to low doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) alters reproductive development in female Long Evans hooded rat offspring. Toxicology and Applied Pharmacology, 146, 237-244. [Pg.428]

Reproductive toxicity of acesulfame K was studied in test systems aimed at detecting teratogenicity, oral embiyotoxicity and in a multigeneration study. No teratogenicity, no embryotoxicity, and no effects on reproduction, development of the fetuses and lactation performance were found.7... [Pg.235]

In earlier chapters, we discussed the discovery of new drugs. After a lead compound has been identified, it is subjected to a development process to optimize its properties. The development process includes pharmacological studies of the lead compound and its effects on toxicity, carcinogenicity, mutagenicity, and reproductive development. These data are important for determining the safety and effectiveness of the lead compound as a potential drug. [Pg.137]

The KS mutations were identified in the KAL gene and result in abnormal olfactory bulb development (99,100). The mutations responsible for the X-linked IHH with adrenal hypoplasia congenita were identified in the DAXl gene. DAXl encodes an orphan nuclear hormone receptor that regulates portions of reproductive development (101,102). [Pg.124]

Foster PM (2006) Disruption of reproductive development in male rat offspring following in utero exposure to phthalate esters. Int J Androl 29 140-147... [Pg.333]

EPA (2010) Atrazine disrupts reproductive development and function across vertebrate classes. http //www.savethefrogs.eom/actions/pesticides/images/publlcatlons/Hayes-EPA-2010-Submission.pdf. Accessed 2011... [Pg.393]

Kraft mill using 100% CIO2 Fish populations Changes in the reproductive development - reduction in gonad size, depression of sex hormones following exposure to bleach effluents subjected to secondary treatment Munkittricketal., 1997 [30]... [Pg.466]

Exposing young male prairie deer mice, Peromyscus maniculatus, to soiled bedding from adult male conspecifics retards the growth of their testes and seminal vesicles. Male, but not female, urine applied to the nose has the same effect. Removal of the olfactory lobes at the age of 3 weeks blocks this effect (Lawton, 1979). The reproductive development of male California voles, M. californicus, is suppressed hy chemical cues from the mother (Rissman etah, 1984). [Pg.212]

Reasner, D. S. and Johnston, R. E. (1988). Acceleration of reproductive development in female Djungarian hamsters by adult males. Chemical Senses 13,729. [Pg.503]

Gray LE Jr, OstbyJ, Ferrell J, et al A dose-response analysis of methoxychlor-induced alterations of reproductive development and function in the rat Fundam Appl Toxicol 12 92-108, 1989... [Pg.445]

Tou, J.C., Chen, J., and Thompson, L.U., Flaxseed and its lignan precursor, secoisolariciresinol diglycoside, affect pregnancy outcome and reproductive development in rats, J. Nutr., 128, 1861, 1998. [Pg.358]

Reproductive development and function depend on endocrine communication throughout the mammalian life cycle. Protein and steroid hormones, growth factors and other signalling molecules affect gene expression and protein synthesis in target cells of different tissues. In particular, fetal development, development of the reproductive tract,... [Pg.54]

Cooper RL Kavlock RJ (1997) Endocrine disruptors and reproductive development a weight-of-evidence overview. J Endocrinol, 162 159-166. [Pg.143]

Lindsey S Wilkinson MF (1996) Homeobox genes and male reproductive development. J Assist Reprod Genet, 13 182-192. [Pg.153]

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See also in sourсe #XX -- [ Pg.132 ]



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