Release of macromolecules from

YH Bae, IC Kwon, CM Pai, SW Kim. Controlled release of macromolecules from electrical and chemical stimuli-sensitive hydrogels. Makromol Chem, Macromol Symp 70 173-177, 1993. 

L.R.Brown, C.L.Wei and R.Langer,/ vivo and in v/ft-o release of macromolecules from polymeric drug delivery... 

R.Langer and J.Folkman, Sustained release of macromolecules from polymers, in R.J. Kostelnik (ed.), Polymeric Delivery Systems, Gordon and Breach, New York, 1978. 

D.S.T.Hsieh, C.C.Chiang, D.S.Desai, Controlled release of macromolecules from silicone elatomer, Pharm. Technol., 6,39-49 (1985). 

The controlled release of macromolecules from non-erodible, hydrophobic polymeric matrices is modelled as a discrete diffusion process with the release of solute occuring through distinct pores in the polymer which are formed as solid particles of molecule dissolve. In order to formulate predictive models of the release behavior of these devices, quantitative information on the microgeometry of the system is required. We present a computer-based system for obtaining estimates of the system porosity, isotropy, particle shape, and particle size distribution from observations on two-dimensional sections from the polymer matrix. 

Kaewvichit, S. Tucker, I.G. The release of macromolecules from fatty acid matrices complete factorial study of factors affecting release. J. Pharm. Pharmacol 1994, 46, 708-713. 

Bawa, R., et al, An explanation for the controlled release of macromolecules from polymers. Journal of Controlled Release, 1985, 1, 259-267. 

Dang, W. and W.M. Saltzman, Controlled release of macromolecules from a biodegradable poly anhydride matrix. Journal of Biomaterials Science, Polymer Edition, 1994, 6(3), 291-311. 

Brown, L.R., C.L. Wei, and R. Langer, In vivo and in vitro release of macromolecules from polymeric drug delivery system. Journal of Pharmaceutical Research, 1983,72, 1181-1185. 

Ho, H.-O., C.-C. Hsiao, T.D. Sokoloski and C.-Y. Chen, Fibrin-based drug delivery systems III The evaluation of the release of macromolecules from microbeads. Journal of Controlled Release, 34 (1995) 65-70. 

Kwon, G.S., Y.H. Bae, H. Cremers, J. Feijen and S.W. Kim, Release of macromolecules from albumin-heparin microspheres,/oitTOfll of Controlled Release, 79 (1992) 191-198. 

Tomer R, Dimitrijevic D, Florence AT. Electrically controlled release of macromolecules from cross-linked hyaluronic acid hydrogels. J Control Release. 1995 33 405-13. 

Dang, W. and Saltzman, W.M., Controlled release of macromolecules from a biodegradable polyanhydride matrix. J. Biomater. Sci., Polym. Ed., 1994,6 291-311. 

Hsieh, D.S.T., Danger, R., Folkman, J. Magnetic modulation of release of macromolecules from polymers. Proc. Natl. Acad. Sd. U.S.A. 78,1863-1867 (1981)... 

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