Regenerative capability

Fernandez-Aviles F, San Roman JA, Garcia-Frade J, Fernandez ME, Penarrubia MJ, de la Fuente L, Gomez-Bueno M, Cantalapiedro A, Fernandez J, Gutierrez O, Sanchez PL, Hernandez C, Sanz R, Garcia-Sancho J, Sanchez A. Experimental and clinical regenerative capability of human bone marrow cells after myocardial infarction. Cite Res 2004 95 742-748. 

Fernandez-Aviles F San Roman JA, Garcia-Frade J, et al. Experimental and clinical regenerative capability of human bone marrow cells after myocardial infarction. Circ Res 2004 95 742-748. 

Obviously, the ease with which the enzyme support can be reclaimed and enzyme activity re-immobilized will make a significant contribution to the cost of bioreactor operation. The higher the initial cost of the support matrix, the more important this regenerative capability becomes. Thus, future development of well defined, stable enzyme supports may depend upon concomitant development of efficient, high affinity, and selective adsorption techniques to allow simultaneous isolation and immobilization. 

The maternal capacities that provide a homeostatic environment and metabolic deactivation of potential toxicants, along with the repair and regenerative capabilities of the embryo/fetus, are believed to impart a threshold phenomenon to developmental toxicity. The supposition of a threshold implies that a maternal dose exists at which a toxicant will elicit no adverse effect on the conceptus. This is in contrast to the threshold principle of carcinogenesis, which assumes that exposure to any amount of carcinogen, even a single molecule, can potentially lead to cancer. 

Liver Fibrosis Liver fibrosis is a common end result of inflammation and/or necrosis. While the liver does have considerable regenerative capabilities, cytokine release associated with the inflammatory/necrotic process can lead to fibrosis that can have a deleterious effect on hepatic function, not only from the aspect of decreased hepatic functional mass but also from the standpoint of compromising blood supply. Animal models of hepatic fibrosis would be valuable from the standpoint of facilitating the development of noninvasive biomarkers as well as development of interventional agents. 

Due to the regenerative capability of bone defects, it is typical in tissue engineering research to consider critical sized defects. The critical size of the defect (CSD), defined as the smallest size that does not heal by itself if left untreated over a certain period of time, is 15 mm in diameter for adult New Zealand white rabbit calvarial defect model. The rat calvarial model is also popular with a CSD of 8 mm in diameter. A bone biomimetic device consisting of a porous biodegradable scaffold of poly(DL-lactide) and type I collagen, human osteoblast precursor cells, and rhBMP-2 was shown to promote bone regeneration in this... 

Silicon carbide whisker-mediated transformation Silicon carbide aystals with a diameter of 0.6 tun and a length of 10-80 jun are mixed in liquid medium by vortexing in the presence of DNA and plant cells. The aystals pierce the cell walls and facihtate DNA transfer into plant cells (Kaeppler et al., 1990). This technique is considered to be one of the simplest techniques of DNA transfer to plant cells it is easy and quick but has a limited use due to low transformation efficiency, damage to cells that affects their regenerative capability, and the health hazards associated working with asbestos and silicon fibers. This technique has been successfully demonstrated in species such as maize, wheat, tobacco, etc. 

Photocontrol ofAnthocyanins and Flavonoids Accumulation in Tomato Seedlings Photocontrol of Nuclear Structure of Tomato Hypocotyl Photocontrol of Regenerative Capability from Tomato Hypocotyl Photocontrol of Stem Elongation of Green Mature Tomato Plants Phytochrome and Tomato Fruit Ripening... 

Photocontrol of Regenerative Capability from Tomato Hypocotyl... 

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