Rapid complex

As to the choice of anticoagulant, citrate is preferred to oxalate, because factor V is more stable in citrate than in oxalate. In addition, citrate rapidly complexes with calcium, forming a soluble complex, in contrast to the slow formation of the insoluble complex of calcium with oxalate (100). 

Bowtell, D. D., and W. Y. Langdon. The protein product of the c-cbl oncogene rapidly complexes with the EGF receptor and is tyrosine phosphorylated following EGF stimulation. Oncogene. 11 1561-1567.1995. 

All the kinetic experiments discussed thus far have been in the gas phase, whose advantages include the possibility of studying the effects of energy release through pressure-dependence studies, and the absence of complications due to solvents, such as the rapid complexation of silylenes. 

With these anthracene-linked dimeric cinchona-PTCs, the Najera group investigated the counterion effect in asymmetric alkylation of 1 by exchanging the classical chloride or bromide anion with tetrafluoroborate (BF4 ) or hexafluorophosphate (PF6-) anions (Scheme 4.10) [17]. They anticipated that both tetrafluoroborate and hexafluorophosphate could form less-tight ionic pairs than chloride or bromide, thus allowing a more easy and rapid complexation of the chiral ammonium cation with the enolate of 1, and therefore driving to a higher enantioselectivity. However, when... 

In Chapter 1 the broad statement is made that the rates of metal complexation reactions are generally high. A more refined conclusion can be drawn from Table 2.3, which lists the time scales over which a number of complex formation and dissociation reactions occur that are important in soil solutions and other natural waters.7 Perusal of these data makes clear the point that although they are usually very rapid, complexation reactions do span a time scale ranging over at least 10 orders of magnitude. Thus the kinetics of these reactions can be very important to understanding the aqueous speciation of metals and ligands in detail. 

As a result of our earlier investigations, we anticipated that rapid complexation should occur between the organometallic reagent and the enone substrate involving... 

Radiotracer experiments, using and Needle s Eye humic substances have also shed light upon changes in U binding which take place following an initial, fairly rapid complexing step. The pattern represents the end result of a long... 

Complexation of a polymer main chain by CDs differs significantly from complex-ations of polymer side chains. Complexations of side chains occur in parallel, while complexation of a main chain is a serial process in which consecutive steps are dependent on each other. Since complexation of a main chain polymer, so-called threading, requires a one-dimensional transport of CD rings along the chain, it requires much more time than complexation of a side chain polymer. While the first segments of a polymer chain are rapidly complexed, migration along the polymer is slow and a molecular version of a traffic jam can occur. 

The polymers that are rapidly complexed by a-CD also dissociate rapidly. Those polymer ICs, like those of ionenes, which require high temperatures and long threading times to be formed, are almost kinetically stable at r.t. 

Fig. 32 Rapid complexation of P22 by Me-P-CD. Transmittance as a function of temperature for an aqueous solution of polymer/Me-P-CD complex P22a at a heating/cooling rate of 1°C min-1. [P22a] = lOOg L 1 (13.75g L 1 polymer, 86.25g L-1 Me-P-CD)...

As mentioned earlier, the proton NMR spectra of small molecules oriented in nematic liquid crystals become rapidly complex with the increase of number of interacting nuclei. In order to obtain information on orientation and structure, it is therefore essential to develop strategies to interpret such spectra with the help of special techniques. Techniques such as Automatic Analysis and the use of Multiple Quantum Spectroscopy have been employed for these purposes during the period under report. A method based on the Automatic Analysis of Multiple Quantum proton spectra of flexible molecules dissolved in liquid crystalline phases has been suggested for extracting starting parameters for the... 

In all systems that contain at least one Cl atom per titanium-aluminum system, there is rapid complex formation, which can be recognized by color intensification (Scheme 1). 

A specific rate constant for the rapid complexation of Ag" ion by thiosulphate ion in aqueous solution has been determined, using the recently developed laser optical-acoustic technique for measurement of sound absorption. In aqueous solution the predominant complexed species is the 1 2 ion [Ag(8203)2] ". 

Rapid Complex Admittance Measurements. The voltage clamp system, chamber, and axial electrode techniques were described previously (10, 12). By superposing a repetitive small-amplitude (1-mV root mean square) Fourier-synthesized signal (8, 16, 19) onto large step clamps, a current response was acquired during voltage clamp pulses. Immediately... 

M. Orchin University of Cincinnati) Some very recent work done in our laboratory by Lawrence Kirch strongly suggests that an olefin-hydrocarbonyl complex is the important intermediate in the oxo synthesis. This new evidence was made possible by the experimental technique of quenching the hot, pressured autoclave in dry ice and releasing the gases below — 50°. The results of this work (1) show that (a) dicobalt octacarbonyl is rapidly converted to cobalt hydrocarbonyl (6) the hydrocarbonyl is rapidly complexed by olefin (c) when the olefin is consumed by normal oxo reaction, the cobalt again appears as the hydrocarbonyl (d) the extent of conversion of dicobalt octacarbonyl to cobalt hydrocarbonyl is dependent on the hydrogen partial pressure. 

It appears there is an initial rapid complex formed between the enzyme and inhibitor which is still active (110). Then, a much slower conformational change occurs (109,110) leading to loss of activity. 

The acute toxicity of silver to aquatic species varies drastically by the chemical form and correlates with the availability of free ionic silver. In natural aquatic systems, ionic silver is rapidly complexed and sorbed by dissolved and suspended materials that are usually... 

The presence of heteroatoms like oxygen or nitrogen in the monomer causes rapid complexation with the organometallic compounds. For instance, when butyllithium initiates polymerization of styrene in hydrocarbon solvents, there is an induction period and the overall reaction is slow and sluggish. When, however, it initiates polymerization of o-methoxystyrene under the same conditions, there is no induction period and the reaction is rapid. This is due to the initiator coordinating with the oxygen atom... 

Scaffold diversity is an important parameter to characterize any compound collection. Organic synthesis is expected to provide efficient approaches to create three-dimensionally complex and structurally diverse small molecules. Branching pathways in DOS is an elegant approach to access scaffold diversity that could lead to small, yet diverse, focused compound libraries. Branching cascades strategy has successfully demonstrated the power and application of cascade or domino reactions in compound collection synthesis to build rapidly complex scaffolds for library synthesis. Further synthesis endeavors toward branching pathways... 

Perform repetitious acts Quickly recognize and correct problems Perform rapid, complex computations Operate in poor environment Use improper tools... 

Requiring operator to perform rapid, complex computations... 

The reaction between cobaIt(u) and pyridine-2-aldoxime takes place in several steps. The initial rapid complex formation is followed by a rate-determining redox reaction where oxidation of the cobalt(n) by the ligand provides a route to an inert cobalt(ra) species. The mode of reaction of some chromium(iii)-bound pyrazine radicals with cobalt(iii) complexes has been clarified. In the reaction shown in equation (3) the green complexed radicals formed have been... 

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