Protecting strategy

Critical to hazard characterization is the identification of hazards and the assessment of possible worker exposure. This can be accomplished in a variety of ways. As described before, one commonly used technique is a JHA with project teams that include the worker. The information collected is used by the SSHO and the radiation control officer to develop an appropriate hazard control and protection strategy. 

An obvious outcome of the Hantzsch synthesis is the symmetrical nature of the dihydropyridines produced. A double protection strategy has been developed to address this issue. The protected chalcone 103 was reacted with an orthogonally protected ketoester to generate dihydropyridine 104. Selective deprotection of the ester at C3 could be accomplished and the resultant acid coupled with the appropriate amine. Iteration of this sequence with the C5 ester substituent ultimately gave rise to the unsymmetrical 1,4-dihydropyridine 105. 

Developments of protection strategies in peptide synthesis have led to the introduction of a wider variety of protecting groups for different functionalities and provide orthogonal protection to specific side chains (Table 1). 

Side reactions in SPPS can still occur even though global protection strategies are used. These side reactions can be residue- or sequence-specific and their intervention depends upon many factors. 

In order to realize the precise control of core/shell structures of small bimetallic nanoparticles, some problems have to be overcome. For example, one problem is that the oxidation of the preformed metal core often takes place by the metal ions for making the shell when the metal ions have a high-redox potential, and large islands of shell metal are produced on the preformed metal core. Therefore, we previously developed a so-called hydrogen-sacrificial protective strategy to prepare the bimetallic nanoparticles in the size range 1.5-5.5nm with controllable core/shell structures [132]. The strategy can be extended to other systems of bi- or multimetallic nanoparticles. 

Supplement and Crop Protection Strategies. International Patent application 97044713, Aberdeen University. 

Yeh, J., and Fernandez, D. 2004. Patent protection strategies for biotechnological inventions. Assay and Drug Development Technologies 2(6), 697-702. 

A more versatile A-protection strategy is seen in Muchowski s A-TIPS-pyrrole (6) [17-19]. Whereas bromination of IV-trimethylsilylpyrrole gives almost exclusively C-2 attack, the NBS bromination of 6 affords the C-3 product 7 in a 96 4 ratio (C-3/C-2) in 93% yield. Deprotection... 

Foster, S. S. D. 1987. Fundamental concepts in aquifer vulnerability, pollution risk, and protection strategy. In Vulnerability of soil and groundwater to pollutants, ed. W. Van Duijvenbooden and H. G. van Waegeningh. The Hague TNO Committee on Hydrological Research. 

Establish a network protection strategy based on the principle of defense-in-depth. 

Scheme 4.17 Immobilized lanthanide-based Lewis acid (31) as tool for selective protection strategies of 1,3-diols.

Notice how the protective strategies are first classified into three categories appearance, chemicals, and armor. Each of these categories is then further classified for analysis. Appearance, for example, is broken down into three types of protection strategies camouflage, warning colors, and mimicry. 

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