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Sugars protection strategies

The somatostatin analogues TATE and Sugar-TATE were synthesized by SPPS techniques following standard Fmoc/Boc protection strategies (see Fig. 6.3) [6.16]. The Fmoc-Asn(Ac4-P-D-Glc)-OH building block [6.14] was used for elongation of the linear protected and resin immobilized TATE sequence. This precursor was synthesized successfully in solution (see Fig 6.2). ES-MS were found to be consistent with the expected formulas. [Pg.95]

New Synthetic Methods Emphasizing Deoxyfluoro Sugars and Protective-Group Strategy... [Pg.2]

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