3- -2-propenyll

Tricarbonyl(chloro)cyclopentadienylmolybdenum 6 reacts with 3-bromo-l-propene under phase transfer conditions at 45 °C to give directly the dicarbonyl(j)3-2-propenyl) complex 8 whereas at lower temperature the tricarhonyl(>/I-2-propenyl) complex 7 is obtained14. It was proposed that the carbon monoxide acts as the reducing agent. 

Rapid distillation is required to avoid a [3,3]-sigrnatropio rearrangement, which gives Ar-allylthiazolidinc-2 thione [2 Thiazolidino-thione, 3-(2-propenyl)-]. 

One of the diastereotopic lone pairs at sulfur in l,7,7-trimethyl-exo-3-(2-propenyl-thio)bicyc1o[2.2.1]heptan-exo-2-ol can be oxidized selectively to yield the corresponding (55)-sulfoxide 7119. 

An excellent laboratory procedure has also been published for the preparation of diethyl (+)-(25,3T )-3-(2-propenyl)-2-hydroxybutanedioate17. For other examples see Tables 1-3. 

The ( /4-bicyclo[2.2.1]hepta-2,5-diene)bis( /3-2-propenyl)ruthenium(II) and (>/4-cycloocta-l,5-diene)bis(>/3-2-propenyl)ruthenium(II) complexes have previously been reported,5,6 but we present here scaled-up procedures that produce synthetically useful quantities of these compounds. The preparation of Grignard reagents is based upon the methods described by Eisch.7... 

The one-stage transformation of 3-butenyl-l-methyl ketoxime (63) to 2-methyl-3-(2-propenyl-l)pyrrole (64) and 2-methyl-3-(l-propenyl-l)-l-vinylpyrrole (65) (Scheme 34) (82TL5063) is typical and demonstrates two essential features of this version of the reaction the reaction either can be stopped selectively at the stage of pyrrole ring formation without vi-nylation onto the N—H bond and prototropic isomerization of the alkenyl, or it can form an N-vinylpyrrole in which the double bond of the alkenyl is shifted into conjugation with the pyrrole ring. 

Ene reaction or dimerization competed with the Diels-Alder cycloaddition when 3-(2-propenyl) Af-substituted indoles 136 were employed as diene systems toward NPMI (88HCA467). On the other hand, with /3-substituted 3-vinyl-l//-indoles 137 and the same dienophile, the products include carbazole derivatives and Michael adducts (Scheme 5) (87HCA1419). 

Therapeutic Function Anticonvulsant, Antiepileptic Chemical Name 2,4-Oxazolidinedione, 5-methyl-3-(2-propenyl)-Common Name Allomethadione, Aloxidone Structural Formula ... 

DIASTEREOSELECTIVE a-ALKYLATION OF g-HYDROXYCARBOXYLIC ESTERS THR0U6H ALKOXIDE ENOLATES (+)-DIETHYL (2S,3R)-3-ALLYL-2-HYDROXYSUCCIMATE FROM (-)-DIETHYL S-MALATE (Butanedlolc acid, 2-hydroxy-3-(2-propenyl)-, diethyl ester, [S-(R,S)])... 

Intramolecular nitrone-alkene cycloaddition. Reaction of cycloalkanones substituted by a 3-(2-propenyl) or a 3-(3-butenyl) side chain with alkylhydroxylamines with azeotropic removal of water results in a bridged bicycloalkane fused to an isoxazolidine ring. The transformation involves formation of a nitrone that undergoes intramolecular cycloaddition with the unsaturated side chain. 

Methyl-4-oxo-3-(2-propenyl)-2-cyclopenten-l-yl 2,2-dimethyl-3-(2-methyl-l-propenyl)... 

S,5/f)-Dihydro-5-iodomethyl-3-(2-propenyl)-2(3//)-furanone (6) Typical Procedure38 ... 

R,5R,6S)-4-tert-Butoxycarbonyl-5,6-diphenyl-3-(r-prop-2 -enyl)morpholin-2-one 4-Morpholinecarboxylic acid, 2-oxo-5,6-diphenyl-3-(2-propenyl)-, 1,1-dimethylethyl ester, 3R-... 

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