Propanamide

Based on IPA, N-H, and N-substituted indole-3-propanamide derivatives (Fig. 11) have been prepared and their efficiencies were investigated towards SOD and LP. Compounds have very significant activity on inhibiting SOD as well as LP [125]. 

Fig. 11 Chemical structure of N-H and AT-substituted indole-3-propanamide derivatives [125]...

Pyrrole-2-carboxaldehyde, P-20181 l//-Pyrrole-2,5-dicarboxylic acid, P-10179 l//-Pyrrole-3-propanamide, in P-30175 l//-Pyrrole-3-propanoic acid, P-30175 2-(l-Pynolin-2-yl)pyridine, D-30124 Pyrrolostatin, see D-20224... 

E. Siddalingamurthy, K. M. Mahadevan, T. O. S. Kumar, Synth. Commun. 2013, 43, 3153—3162. Choline chloride/ urea ionic liquid eatalyzed a eonvenient one-pot synthesis of indole-3-propanamide derivatives. 

Methyl-2-(o-phenylazopbenoxy)propanamide (Chart 9). Cleaved by reduction. 

Pharmaceutical Manufacturing Encyclopedia Chemical Name 3-chloro-N-(phenvlmethyl)propanamide... 

Chemical Name 2-Methyl-N-[4-nitro-3-(trifluoromethyl)phenyl] -propanamide Common Name Niftolid... 

Chemical Name N-(2-methylphenyl)-2-(propylamino)-Propanamide hydrochloride Common Name Propitocaine hydrochloride... 

Answer Problem 21.37 for reaction of the listed reagents with propanamide. 

N-protected aminoacids 14 behave as carboxyl partners in Ag20 promoted reactions of 2-bromo-isobutyramides or -propanamides affording, respectively, esters of 2-hydroxy-isobutyramides (ref. 20a) or lactamides 15 (ref. 20b). While we plan further research on stereochemical and other aspects of these reactions, model units obtained from 2-bromo-isobutyramides have been used in conformational studies of depsi-peptides (ref. 21). 

Many 2-bromoamides were tested for toxicity or mutagenicity 2-bromo-N-benzyl-propanamide showed mutagenic effects, unrelated to its configuration (ref. 25). 

CijHisBrO, 92905-04-9) see Domiodol 2-bromo-lV-(2-methylphenyl)propanamide (C nH 2BrNO 19397-79-6) see Prilocaine... 

A -methyl-9,10-ethanoanthracene-9(10ll)-propanamide (C20H21NO 23716-34-9) see Maprotiline [liJ-[ltt,5a,6(7J )]]-a-(l-methylethenyl)-7-oxo-3-phenyl-4-oxa-2,6-diazabicyclo[3.2.0]hept-2-ene-6-acetic acid diphe-nylmethyl ester... 

Diethyl ether, methyl n-propyl ether, diethylamine, N-methyl-1 -propanamine, acetone, allyl alcohol, dimethylformamide, propanamide, 2-methylpropan-amide, 2,2-dimethylpropanamide, benzamide, dichloromethane, toluene, ethyl N-acetyl-glycinate, -alaninate, -methioninate, and -aspartate, ethyl acetate, tetrahydrofuran... 

Additional observations reflect on the high stability of the DTU host lattice and illustrate its versatile capability to form clathrates with different guests. The crystalline 1 1 complexes of DTU with diethylether (Fig. 29) and diethylamine are isomorphous with the structure of the propanamide adduct (Fig. 24). However, in these structures the hydrogen bonds do not form a continuous pattern but are, rather, confined to... 

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