Promoters vascular endothelial growth factor receptors

Bachelder RE, Wendt MA, Mercurio AM. Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4. Cancer Res 2002 62(24) 7203-7206. 

Growth factors bind to receptors on the cell surface and subsequently activate cellular proliferation or differentiation. Many growth factors stimulate cellular division in numerous cell type, whereas others are specific to particular cell types. They often promote cell differentiation and maturation, whereas varies between growth factors. For example, bone morphogenic proteins stimulate bone cell differentiation, whereas vascular endothelial growth factors stimulate blood vessel differentiation. 

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