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Product realisation

Planning of product realisation - Plan and develop process for product manufacture based on risk analysis, and determine verification, validation, monitoring test and inspection requirements... [Pg.232]

In pharmacy preparation the very first step of Product realisation is the prescription assessment for an individual patient or the benefit/risk assessment (and definition of indications) for a stock preparation. See Sect. 2.2 for the performance of this step and for the assignment of responsibilities. [Pg.784]

Note 1. Aqueous work-up and extraction with diethyl ether can also be carried out but will take longer. In the proposed procedure the distilled reaction product is collected in a cooled receiver if no cooling is applied, the required pressure of 10-15 mnHg cannot be realised because of tlie presence of volatile components and water in the reaction mixture. [Pg.135]

Using a solution process, the choice of catalyst system is determined, among other things, by the nature of the third monomer and factors such as the width of the mol wt distribution to be realised in the product. A number of articles review the induence of catalyst systems on the stmctural features of the products obtained (3,5—7). The catalyst comprises two main components first, a transition-metal haHde, such as TiCl, VCl, VOCl, etc, of which VOCl is the most widely used second, a metal alkyl component such as (C2H )2A1C1 diethylalurninum chloride, or monoethyl aluminum dichloride, (C2H )AlCl2, or most commonly a mixture of the two, ie, ethyl aluminum sesquichloride, [(C2H )2Al2Cl2]. [Pg.503]

The use of fire retardants in polymers has become more complicated with the realisation that more deaths are probably caused by smoke and toxic combustion products than by fire itself. The suppression of a fire by the use of fire retardants may well result in smouldering and the production of smoke, rather than complete combustion with little smoke evolution. Furthermore, whilst complete combustion of organic materials leads to the formation of simple molecules such as CO2, H2O, N2, SO2 and hydrogen halides, incomplete combustion leads to the production of more complex and noxious materials as well as the simple structured but highly poisonous hydrogen cyanide and carbon monoxide. [Pg.149]

As mentioned in Section 22.1 the probability of acetylation of any one cellulosic group is strongly dependent on its position in the fibre. Since they cannot be dissolved before acetylation it will be realised that some molecules will be completely acetylated whilst others may be untouched. It is thus necessary first to acetylate completely the cellulose and the resultant triacetate material, which is soluble in certain solvents, may then be back-hydrolysed in solution. Under these conditions the probabilities of hydrolysis of any acetyl groups in one molecule will be similar to the reaction probabilities of these groups in another molecule and products with a reasonably even degree of substitution less than three may be obtained. [Pg.621]

The formation of a single complex species rather than the stepwise production of such species will clearly simplify complexometric titrations and facilitate the detection of end points. Schwarzenbach2 realised that the acetate ion is able to form acetato complexes of low stability with nearly all polyvalent cations, and that if this property could be reinforced by the chelate effect, then much stronger complexes would be formed by most metal cations. He found that the aminopolycarboxylic acids are excellent complexing agents the most important of these is 1,2-diaminoethanetetra-aceticacid (ethylenediaminetetra-acetic acid). The formula (I) is preferred to (II), since it has been shown from measurements of the dissociation constants that two hydrogen atoms are probably held in the form of zwitterions. The values of pK are respectively pK, = 2.0, pK2 = 2.7,... [Pg.55]

The realisation that yeasts would produce dtric acid from n-paraffins was veiy attractive in the late 1960 s. Petroleum byproducts were plentiful and very cheap and there was detailed knowledge available on these processes because the use of hydrocarbon-utilising yeasts for single cell protein was well developed. The strategy was to use n-alkane to produce high yields erf dtric add-producing Candida spp. and to harvest two useful end products rather than just one. The process has not been commerdally successful however. Candida spp. produce mixtures of dtric add and isodtric add and the latter is not a useful product. In addition, since 1973 when petroleum prices rose sharply and have in fact continued to rise, the n-paraffins are no longer a cheap substrate. [Pg.126]

In this description we have made a clear distinction between growth and secondary product synthesis. You should, however, realise that the distinction is not quite so sharp in practice. Thus we might expect some, albeit a small amount, of secondary product formation in file trophophase and some growth of new cells replacing dead ones in the idiophase. Nevertheless, the separation of the process into two phases enables the optimisation of conditions for growth in one phase and the imposition of conditions which maximise production of antibiotic in the other. [Pg.161]

The monomer, styrene, is a derivative of benzene, vinyl benzene (1.2). It is a colourless, mobile liquid that polymerises readily. The first report of the polymerisation reaction came in 1839, when E. Simon described the transformation of what was then called styrof. He believed he had oxidised the material and called the product styrol oxide. Later, when it was realised that it contained no oxygen, the product became known as metastyrene. [Pg.9]


See other pages where Product realisation is mentioned: [Pg.184]    [Pg.232]    [Pg.2]    [Pg.10]    [Pg.174]    [Pg.769]    [Pg.784]    [Pg.784]    [Pg.792]    [Pg.184]    [Pg.232]    [Pg.2]    [Pg.10]    [Pg.174]    [Pg.769]    [Pg.784]    [Pg.784]    [Pg.792]    [Pg.195]    [Pg.331]    [Pg.346]    [Pg.964]    [Pg.728]    [Pg.480]    [Pg.1]    [Pg.78]    [Pg.44]    [Pg.90]    [Pg.77]    [Pg.85]    [Pg.270]    [Pg.260]    [Pg.749]    [Pg.861]    [Pg.234]    [Pg.232]    [Pg.950]    [Pg.54]    [Pg.55]    [Pg.34]    [Pg.297]    [Pg.308]    [Pg.991]    [Pg.86]    [Pg.127]    [Pg.179]    [Pg.182]    [Pg.298]   
See also in sourсe #XX -- [ Pg.784 ]




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