Product configurator Subject

Industry estimates indicate that up to 5% of the total resin production finds its way into prototype or mill shape plastic products. By mill shapes is meant those primary uniform configuration subject to established cross-sectional and length tolerances. While this estimate is necessarily conjectural, the best available information indicates that this range is accurate. Modem Plastics magazine estimated mill shape production for 1968 in acrylics, cellulose, nylon, acetal, polycarbonate, high density polyethylene, polypropylene, poly(vinyl chloride), and copolymers to approach 336.4 million pounds. Total United States resin production for 1968 slightly exceeded 16 billion pounds. 

The structural elucidation of the secondary metabolites of Dictyosteiiium cellular slime molds was achieved by Y. Oshima et al. The total synthesis of a novel compound, dictyopyrone A, which possesses a unique a-pyrone moiety with a side-chain at the C3 position, was successfully carried out using the maionic ester synthesis. Meldrum s acid was acylated and the product was subjected to transesterification with an optically active did. Specific rotation of the final product was identical with that of the natural product, so the absolute configuration was established as (S). 

In the laboratory of T. Nakai, the asymmetric tandem Claisen-rearrangement-ene reaction sequence followed by a modified McMurry coupling was used to access (+)-9(11)-dehydroestrone methyl ether. The Claisen-ene product was subjected to ozonolysis and epimerization to the 8,14-anf/ configuration. The C-ring was constructed by treating the tricyclic diketo aldehyde with TiCl3-Zn(Ag) in DME to afford the desired final product in 56% yield. 

The EtOAc-soluble fraction of the alkaline hydrolysate of 37 containing a mixture of fatty acid units was treated with ozone followed by NaBH4 reduction. Trimethylsilyl (TMS) derivatives of the ozonolysis product were subjected to chiral CjC analysis (Chirasil-Val) to give a p identical with the TMS-derivative of (i0-l 2-propanediol. Consequently, the absolute configuration of C-9 " position of 37 was assigned as S. 

Thirty subjects were randomly assigned to an evaluation segment (five subjects to each of the six test configurations). Subjects underwent a 7-day pretrial restriction period during which they avoided skin contact with products and/or processes known to affect the normal microbial populations of the skin. 

The steady-state simulation of distillation columns in Aspen Plus discussed in previous sections took a rating approach to the problem. Specific values for the total number of trays and the feed-tray location were selected, and the required reflux ratio and reboiler duty were determined for this specific configuration, subjected to attaining the desired product specifications. Then, economics must be used to find what the optimum tray configuration is. 

The optical rotatory dispersion curves of steroidal ketones permit a distinction to be made between the conformations, and assignment of configuration is possible without resorting to chemical methods (see, e.g. ref. 36) which are often tedious. The axial halo ketone rule and, in the more general form, the octant rule summarize this principle and have revealed examples inconsistent with the theory of invariable axial attack in ketone bromination. 2-Methyl-3-ketones have been subjected to a particularly detailed analysis. There are a considerable number of examples where the products isolated from kinetically controlled brominations have the equatorial orientation. These results have been interpreted in terms of direct equatorial attack rather than initial formation of the axial boat form. 

---