Problem in Handling

Many elderly have vision and co-ordination problems. This is problematic for reading and opening containers and package leaflets pour solutions, dripping eye-drops etcetera. Several aids are commercially available and sold at pharmacies. 

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Elevated temperatures are necessary for cure and the chemical resistance of the laminates is inferior to those from unmodified resins. Because of problems in handling, the polyamides have found only limited use with epoxy resins, mainly for coating and adhesive applications. 

For routine studies with the ESR spectrometer, it is most convenient to work at X-band frequencies ( 9.5 MHz or 3 cm). The sample is usually contained in a 4 or 5 mm diameter quartz tube having a sensitive region about 2 cm in length. An alternative frequency is at Q-band ( 35,000 MHz or 1 cm). Here, the cavity dimensions are much smaller and the diameter of the sample tube is less than 2 mm. This creates some problems in handling and degassing powder samples. By varying the frequency it is possible to determine which features in a spectrum are due to Zeeman interactions... 

Safety Problems in Handling Low-Temperature Industrial Fluids, 1964, IChE Symp. papers, published in Chem. Engr., 1965, 43(185), CE7-10 (186), CE36-48... 

The continuous change taking place within the present-day petroleum refining and alternative fuel industries has not diminished the need to solve fuel-related problems as they develop. Even after fuel is processed, problems in handling, transportation,... 

Solvents present special problems in handling since they must be dried and deoxygenated before being introduced into the dry box. Solvent manipulation... 

Gas studies are well covered with extensive explanation and interpretation of experimental data, such as steady state calculations, all illustrated by frequent use of worked examples. Solution kinetics are similarly explained, and plenty of practice is given in dealing with the effects of the solvent and non-ideality. Students are given plenty of practice, via worked problems, in handling various types of mechanism found in solution, and in interpreting ionic strength dependences and enthalpies, entropies and volumes of activation. 

Pteridines are widely distributed in nature and function as pigments, biological markers, and cofactors of enzymatic reactions. The oxidized heteroaromatic forms show a characteristic fluorescence which allows easy detection even in low concentrations. However, the more active 5,6,7,8-tetrahydro derivatives are nonfluorescing and oxidizable and create experimental problems in handling this type of compound. So far, all naturally occurring pteridines have turned out to be derivatives of pterin (2) and lumazine (3) which are modified by different substituents and functional groups in the 6- and/or 7-position. 

Another common chemical which has caused serious problems in handling and transport is calcium hypochlorite. When dry and uncontaminated, the chemical is safe, but even small... 

BLEVE - boiling liquid expansion vapor explosion. The National Fire Protection Association, 470 Atlantic Ave., Boston, MA 02210, has comprehensive literature and training aids on this subject and related problems in handling of hazardous cargoes. 

RNase. Ribonuclease an enzyme which degrades RNA. It is ubiquitous in living organisms and is exceptionally stable. The prevention of RNase activity is the primary problem in handling RNA. 

This equation tells us that both short and long time measurements are important to acquire a full lineshape of D(t) where continuous variation of t is ideal. If our goal is a full-recording of D(t), the best approach is to calculate MSD from the statistical accumulation ofX data, real-time movements (trajectory) of molecules. Therefore, fast detection is better because the MSD in a long period can be obtained from the summation of Ax in any range. However, when Axt becomes short with fast observation, finer spatial resolution is also required. This is the reason why the dilemma between time resolution and spatial resolution still remains a problem in handling the real-time movements of substances in any biological system. 

Proteins are often unstable and may require special handling. For example, they may be especially sensitive to pH, temperature, or salt concentration, among other factors. Problems in handling a protein may become apparent only after considerable time and effort have been expended. For example, the investigation of nitrogenase, the enzyme that catalyzes the reduction of N2 to form NH3, was hindered for years until it was discovered that the enzyme s activity is destroyed by contact with 02. 

One of the problems in handling powdered carbon arises from the difficulty of immersing it in the liquid to be treated. The difficulty is caused by a film of adsorbed gas that is displaced when a liquid wets the carbon. When displaced, the gas tends to carry some of the powdered carbon and thus create dust. The situation is aggravated if the gas is released suddenly, as when the carbon is mixed with a hot liquid, especially a hot oil or wax. Because of this, carbon should be mixed with a liquid at the lowest practicable temperature. 

Nitrogen mustards were selected for the clinical application for the treatment of neoplasms because they presented fewer problems in handling, besides their respective hydrochlorides and other salts are generally stable solids having low vapour pressure and high solubility in water. 

Of course, some problems in handling INS have to be mentioned as well. 

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