Priority reflective

That only the wrong C-16 diastereomer seemed to be produced in this reaction was then demonstrated by the Kutney group, who prepared a series of binary indole-indoline alkaloids using the chloroindolenine approach. The apparent simplicity of this coupling reaction and the rapidity in assembling such binary alkaloids prompted an extensive study of reaction conditions (28), with the desire to find a procedure suitable for generation of the C-16 (S) isomer, required for anticancer activity. Despite the intensive effort involved in this in-depth study, no success could be realized, and it was therefore widely accepted that .. . it is very unlikely that any natural dimer could be obtained in this way (7). At this point it may be noted, however, that we were able to show subsequently that the desired C-16 -C-14 PARF relative stereochemistry can be obtained as a preferential result, albeit only in very low yield [3.6% PARF versus 2.1% PREF (priority reflective)], when the chloroindolenine reaction with vindoline is initiated with silver tetrafluoroborate (13). 

The National Aeronautics and Space Administration (NASA) has long given high priority to missions that ask whether extraterrestrial life might exist in the solar system and beyond. That priority reflects public interest, which was enhanced in the mid-1990s when fragments of Mars delivered to Earth as meteorites were shown to contain small structures reminiscent of microbial life. 

Rules-based distribution planning system Demand priorities reflecting strategic customer relationships as business policies are automatically followed in allocating resources first-in-first-out (FIFO) is utilized as the default scheduling priority l-Customer segmentation and supply chain strategy 0 X X X... 

Demand priorities reflecting strategic 1 - Customer segmentation and o... 

As indicated previously, PSM information and messages have different values for different audiences. Your company s workforce has a more immediate and specific interest in the initiative than people who are less directly affected, such as plant neighbors, shareholders, or the general public. This doesn t mean confining communications efforts solely to company employees it simply suggests that you organize communications priorities to reflect levels of interest and information needs. 

Our approach to research in parallel processing has been, and remains, very pragmatic it reflects our basic priorities, which are to secure a workable parallel processing system as quickly as possible, and begin using it on the large-scale scientific and engineering applications that are central to our research. 

Managing risk and uncertainty was increasingly seen as a priority in recent conferences, reflected in these comments from R D management interviews ... 

The thirtieth volume in the series marks the completion of over three decades of endeavour by more than 170 contributors from laboratories in 19 different countries to bring over 120 selected areas of progress in physical organic chemical research to the attention of readers worldwide. Its publication provides an occasion to thank them and also to reflect on the changing times and priorities of research in this field, and to contemplate the future. 

Acknowledgment and Personal Statement, the selection of material in the examples and schemes does not reflect priority, importance, or generality. It was beyond our capacity to systematically survey the many examples that exist for most reaction types, and the examples included are those that came to our attention through literature searches and reviews. 

Several refineries, tank farms, and other petroleum-handling facilities nationwide are included on the EPA 1996 National Priorities List, or are regulated under RCRA. Such facilities present several potential subsurface environmental concerns, reflecting approximately 80 years of continued operation. These concerns include ... 

The first attempt at soliciting advice for pharmacopeial priorities was the joint issuance of a letter in May 1990 by the USP in English, by the EP in English and French, and by the JP in Japanese [11]. It went to the regulatory agencies and pharmaceutical industry associations in the cormtries and regions served by each of these pharmacopeias. Reflecting the sentiments of the speakers at the 1989 conferences, the letter was devoted to pharmaceutical excipients and asked only three questions. 

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