Pramoxine cream

Phase A Add the cetyl alcohol (item 1) and the cetyl esters wax (item 2) to a suitable jacketed stainless steel tank fitted with efficient agitation. Heat to 60°-65°C and mix until materials are melted and phase is uniform. 

Preheat a suitable jacketed stainless steel batch tank to 60°-65°C. Strain phase A (step 1) into the batch tank, maintaining temperature at 60°-65°C and gentle agitation. 

Phase B Charge 530 mL of purified water (item 3) into a suitable jacketed stainless steel tank fitted with a high-speed mixer. Adjust the water temperature to 80°-90°C and add methylpara-ben (item 4) and propylparaben (item 5). Stir until dissolved, ensuring that no solids are entrained in the bottom valve. Commence cooling to 60°-65°C. 

Add the sodium lauryl sulfate (item 6) with care and stir to dissolve. 

Add the glycerin (item 7) and mix until uniform. Caution Do not create excessive foam. 

---

Cream Pramoxine 1%, hydrocortisone 1% [30 gm] Apply to affected area(s) tid-qid... 

Pramoxine (Anusol Ointment, PrectoFoam NS, Others) [Topical Anesthetic] Uses Relief of pain itching from hemorrhoids, anorectal surg y topical for bums dermatosis Action Topical anesthetic Dose Apply freely to anal area q3h Caution [C, ] Disp Foam (Proctofoam-NS), cream, oint, lotion, gel, pads, spray SE Contact dermatitis, mucosal thinning w/ chronic use EMS None OD Unlikely... 

Pramoxine hydrochloride is a topical anesthetic that can provide temporary relief from pruritus associated with mild eczematous dermatoses. Pramoxine is available as a 1% cream, lotion, or gel and in combination with hydrocortisone acetate. Application to the affected area two to four times daily may provide short-term relief of pruritus. Local adverse effects include transient burning and stinging. Care should be exercised to avoid contact with the eyes. 

Hydrocortisone Acetate and Pramoxine Hydrochloride Cream and Lotion... 

Analpram HC cream 1 % hydrocortisone acetate/1 % pramoxine hydrochloride)... 

---