Potential explored

Amphotericin B is an extremely potent anti-fungal agent used in the treatment of systemic fungal infections. However, delivery of amphotericin B is very difficult due to its insolubility in the water as well as commonly used oils. Furthermore, it shows several adverse effects such as nephrotoxicity. Brime et al. [109] successfully entrapped amphotericin B in the lecithin-based microemulsions and evaluated their acute toxicity in the mice in comparison to the marketed formulation. Acute toxicity studies indicated that 

Zhang et al. have reported formulation of microemulsion of norcanthridin, an anticancer agent used for hepatic cancers [116]. The microemulsions were composed of lecithin, ethanol and ethyl oleate. The mean residence time, area under the curve (drug availability) and the liver concentrations of norcanthridin were significantly higher for the microemulsions as compared to that of the marketed formulation. 

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Mutual exclusivity. In branching from one node to its descendants, we should ensure that none of the subsets overlap with one another otherwise we could potentially explore the same solution subsets in multiple branches of the tree. Formally, if X is the original solution space and x, is the ith subset, then... 

Smee, B.W. 1999 The effect of soil composition on weak leach solution pH a potential exploration tool in arid environments. Explore, 102, 4-7. 

The increased interest in Mo and W due to commodity price increases since 2006 has created a need for a synthesis of information on known deposits and potential exploration environments within the province of Newfoundland and Labrador. This review is drawn from the historical database of exploration and scientific studies, but it also provides some essential geological information concerning recent exploration developments in Newfoundland. Further information is provided in a recent article by Kerr et al. (2009). Molybdenum mineralization also occurs in Precambrian granites in Labrador, but these deposits presently lie within Inuit lands that are... 

Example 8.3 Influence of Capacitance on Linearity While the capacitance for a coated surface may be independent of applied potential, as shown in Figure 5.12, the capacitance for a bare electrode may be a function cf potential. Explore the influence of a potential dependent capacitance on the linearity of the impedance response. 

As far as finding improved catalysts or operating conditions is concerned, a variety of experimental studies have been conducted. Promotion by alkali metal salts [11], especially cesium [12,13], has been shown to increase the EO selectivity. Similarly, it is observed that addition of chlorine to the catalyst results in higher EO selectivity [14-18]. Atmospheric pressure experiments in our laboratory have indicated that Cu-Ag bimetallic catalysts are more effective than pure Ag [19]. Furthermore, it is observed that after addition of Cs and Cl to the Cu-Ag bimetallic catalyst, it outperforms the corresponding promoted silver catalyst [20]. Published experimental studies have t)q)ically focused on a limited number of catalyst components, whereas one could potentially explore a wide variety of catalyst combinations using theoretical tools. 

In the dl region, comparison of the i E) and C E) curves can be used as a first test [one should be able to deduce one from the other, the current being only capacitive, (i = CdE/dt)]. The shape of the minimum (corresponding to the capacity of the diffuse part of the electrochemical dl) on the C(E) and i(E) curves (Fig. 15) for the case of no adsorption in dilute solution, is another criterion it should not be too different than that observed for mercury, but its position in the range of potential can be completely different. The shape of the adsorption peak is another criterion (in the case of adsorption) it should be sharp and reproducible. Of course, the stability and reproducibility of the curves are important and should be observed not only in the dl region but over all the range of potential explored. 

For the (110) face, there is no hysteresis and no effect of the range of potential explored but a secondary effect was also observed. It is easier to observe in concentrated solutions and in the case of specific adsorption (see Section V.2) it does not seem to alter the contribution of the diffuse part of the dl on the C(E) curves. 

Figure 24. C E) curves for the (100) face of gold in 10 mM NaF (frequency of the alternating signal = 20 Hz sweep rate =10 mV s ) for different negative limits of the range of potential explored. ...

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