Poppy seed oil

Mohn, m. poppy, -gewachse, n.pl. (Bot.) Pa-paveraceae. -kapsel, /., -kopf, m. poppy capsule, poppy head. -81, n. poppy-seed oil. molmrot, a. poppy-red. 

Figure 4.10 Mass spectrum of poppy seed oil obtained by DI El MS on a GCQ Finnigan device equipped with an ion trap analyser. Adapted from Regert and Rolando, 2002...

The ratio of palmitic acid to stearic acid (P/S) can be used to differentiate between drying oils, since these two saturated monocarboxylic acids are less subject to chemical reactions during treatment and ageing. Also, they have a similar chemical reactivity, so their ratio can be hypothesized to be relatively unaltered during ageing. The P/S ratio approach was pioneered by Mills [10], and has been subsequently adopted in a number of studies [7 9]. Typical values of the P/S ratio are 1 2 for linseed oil, 2 3 for walnut oil, 3 8 for poppy seed oil and 2.5 3.5 for egg. 

To identify the kind of oil, Keune et al. [2005] used the classical approach based on the palmitic acid/stearic acid (P/S) ratio usually obtained from GC/MS data. Ratios less than 2 correspond to linseed oil, whereas ratios higher than 5 correspond to poppy seed oil. Intermediate values can be attributed to walnut, poppy seed oil or mixtures [Schilliing and Khaijan 1996]. Keune et al. first show that ionization efficiency is the same for the two fatty acids in negative ion mode permitting the use of ToF-SIMS for the calculation of the P/S ratio. A test on the oil-paint model system shows a ratio of 2.0 for linseed oil and 3.6 for poppy seed oil, which can allow the two oils to be differentiated. Nevertheless, it is important to note that the ratio is not constant all over the cross-section. 

Iodine-131-labeled Lipiodol, a polyiodinated poppy seed oil which becomes particulate on dispersion in aqueous media, has been used for some time in treatment of hepatocellular carcinoma by arterial injection. This targeting approach has been coupled with the superior radioactivity properties of rhenium radioisotopes by exploiting the lipid solubility of... 

The first extensively tested RES-specific contrast agent on the basis of iodinated lipids was EOE-13 with its precursors, AG 52-315 and AG 60-99. EOE-13 is an aqueous emulsion of the iodinated ester of poppy seed oil and is able to selectively enhance the normal liver and spleen parenchyma [10-12]. However, severe adverse events such as headache, fever and chills prevented further use of these contrast agents [13-15], although their extent could be decreased by hydrocortisone given prior to contrast injection. 

The basis for contrast agents derived from nutrional products was Intralipid, which had been prepared from phospholipids obtained from soy bean oil and egg yolk [86]. Intralipid was chemically modified by iodination into Intraiodol, which contained 50 mgl mbThe particles formed in the emulsion were mostly taken up by the hepatocytes and to a lesser extent by the RES [87,88]. Intraiodol was better tolerated than EOE-13 or its precursor, AG 60.99. The addition of cholesterol to Intraiodol resulted in NRI 757 with an iodine concentration of 42 mg mL b Further modifications by replacing the iodinated triglycerides of Intraiodol by ethiodized poppy seed oil and reducing the cholesterol content to... 

Goiter due to iodide deficiency is best managed by prophylactic administration of iodide. The optimal daily iodide intake is 150-200 meg. Iodized salt and iodate used as preservatives in flour and bread are excellent sources of iodine in the diet. In areas where it is difficult to introduce iodized salt or iodate preservatives, a solution of iodized poppy-seed oil has been administered intramuscularly to provide a long-term source of inorganic iodine. 

Johansson, A. (1979) The content and composition of sterols and sterol esters in sunflower and poppy seed oils. Lipids, 14(3), 285-291. 

The following oils are recommended in decreasing order of preference, the bracketed numbers indicating the approximate linoleic acid content sunflower-seed oil (60), poppy-seed oil (60), cotton-seed oil (45). 

Cotton seed oil.. Sun-flower oil... Poppy seed oil.. Hemp seed oil... Linseed oil (raw)... 

In 17 of 53 cases with obstructive lymphedema there was an increase in Umb volume after lymphangiography with Lipiodol ultrafluid (iodinated poppy seed oil), and 10 cases had features resembling Ijmphangitis. In one patient there was an allergic reaction, with rapid development of edema and an increase in limb volume by 2 liters. Whereas contrast medium virtually disappears from normal Ijmphatics within 8 hours, in cases of obstructive lymphedema Lipiodol remains in the lymphatics for several days and it appears to cause a low grade chemical inflammation with obliteration of the lymphatics (SEDA-7, 454). 

Compound derived from poppy seed oil. Inhibits oxidation of pyruvic acid, which accumulates in the blood. Used as antimicrobial to control dental disease but also toxic - cause of epidemic dropsy. 

Poppy Oil. Poppy -seed oil. Expressed from poppy seeds. Contains no morphine or other opium alkaloids. 

Olive oil is often illegally adulterated with other less expensive vegetable oils. Oils widely used for this purpose include olive pomace oil, corn oil, peanut oil, cottonseed oil, sunflower oil, soybean oil, and poppy seed oil. °° Among the varions chemical and physical methods employed toward the detection of the adulteration of olive oil by low-grade olive oils and seed oils are (a) Sterol analysis (presence of stigmasterol and 3-sitosterol), (b) alkane analysis (C27, C29, and C31), (c) wax and aliphatic alcohol analysis, (d) fatty acids/(with HPLC) trans fatty acid, and (e) Triacylglycerol. 

Hepatic arterial bland and chemo-embolization have also been utilized. This therapy is based on the anatomic vascular distribution of the blood supply for hepatic tumors. The hepatic artery serves tumors in the liver almost exclusively while the portal vein serves normal hepatic parenchyma. There is some crossover but it is only approximately 10%. Bland embolization uses particles placed in the hepatic artery only while chemoembolization mixes these particles with a variety of chemotherapeutic agents and lipiodol, an iodinated poppy seed oil, which has been shown to increase the uptake into the cell via a pump in the cell wall. This therapy has been utilized for the last 20 years but eventual re-growth and recurrence have also uniformly occurred. Repeated embolizations are necessary to keep the disease in check and to palliate the patient s symptoms. The mean response to embolization is approximately 12-18 months with eventual occlusion of the hepatic arterial supply to the tumor after multiple embolizations. Response to embolotherapy has been dramatic for palliation of symptoms, with 63% of patients reporting a reduction in symptoms and an objective response seen on CT to be 76% either partial or minimal response, with an additional 16% reporting stable disease [4]. The embolotherapy will rid the patient of much of their tumor burden but isolated islets of viable tumor will remain after the procedure, accounting for the resurgence of disease. 

S. Higashi and T. Setoguchi, Hepatic arterial injection chemotherapy for hepatocellular carcinoma with epira-bicin aqueous solution as numerous vesicles in iodinated poppy-seed oil microdroplets Clinical application of water-in-oil-in-water emulsion prepared nsing a membrane emulsification system, Adv. Drug Deliv. Rev. 45 (2000) 57-64. 

Definition Ethyl ester of the iodinated fatty acids expressed from poppy seed oil Uses Emollient in cosmetics, slenderizing prods. 

---