Polymers, biodegradable porous

Another approach to improve the properties of chitosan hydrogels is via the preparation of polymer composites. Porous hydrogels of N-carboxymethyl chitosan/polyvinyl alcohol were prepared by Lee et al. [99]. Hydroxypropyl chitosan was combined with sodium alginate for the formation of biodegradable hydrogels [100]. Chitosan-hyaluronic acid composite was prepared by Tan et al. [101]. 

T. van Tienen, R. Heijkants, R Buma, J. de Groot, A. Pennings, R. Veth, Tissue ingrowth and degradation of two biodegradable porous polymers with different porosities and pore sizes. Biomaterials 23 (8) (2002) 1731-1738. 

Seeding the cell in the biodegradable porous polymer scaffolds... 

Biodegradable porous polymers have been fabricated by the TIPS method from a range of synthetic and natural polymers including gelatin,chit-osan, PLGA, polyurethanes (PU), PCL, and PLLA. Representative SEM images of the structure of such a phase separated porous... 

A method was recently developed to deliver plasmid DNA locally to cells involved in wound repair (Bonadio et al., 1999 Fang et al., 1996 Shea et al., 1999). The technique involves the introduction of a porous, biodegradable polymer matrix into the wound site (Bonadio et al., 1998). The scaffold (a gene activated matrix, or GAM), in its simplest form comprises plasmid DNA and the polymer matrix (Bonadio, 2000). Naked... 

Torres et al. (2006) reported a novel microwave processing technique to produce biodegradable scaffolds for tissue engineering from different types of starch-based polymers. Potato, sweet potato, com starch, and non-isolated amaranth and quinoa starch were used along with water and glycerol as plasticizers to produce porous stmctures. Figure 16.1 shows the manufacturing procedure of microwaved starch scaffolds. 

Porous, biodegradable polymer scaffolds seeded with cells have been used to determine the feasibility of regenerating a number of organs. The goals and specific problems associated with regenerating several different organs are outlined below. 

Rezwan K, Chen QZ, Blaker JJ, Boccaccini AR (2006) Biodegradable and bioactive porous polymer/inorganic composite scaffolds for bone tissue engineering. Biomaterials 27(18) 3413—3431... 

De Ponti R, Torricelli C, Martini A, Lardini E. Use of supercritical fluids to obtain porous sponges of biodegradable polymers for pharmaceutical implants or drug delivery systems. Italy, WO 9109079, 1991. 

---