Polyethylene glycol-coated poly

Nagata et al. reported the use of a polyethylene glycol-coated poly(methyl methacrylate) (PMMA) microchip for microchip gel electrophoresis separations. Trypsin inhibitor, bovine serum albumin (BSA) and 3-galactosidase (labeled with Alexa Ruor 488) were electrokinetically loaded for 60 s. The sodium dodecyl sulfate (SDS)-protein complexes were then separated and baseline resolved in 8 s using a 5% linear polyacrylamide/0.1% (w/v) SDS-based separation buffer, 3 mm separation channel, and 303 V cm electric field. 

To avoid inactivation of the biological molecules in vivo by interaction with blood (or tissue) fluids and by clearance mechanisms, it may be desirable to coat the delivery system with a hydrophilic polymer such as polyethylene glycol and poly-[W-(2-hydroxypropyl)methacrylamide]. 

Wu and Siggia described a dynamic coating technique for the application of a liquid stationary phase - Poly G-300 - on a silica gel support. With heptane - ethanol (10 1) saturated with the stationary phase, strychnine and brucine could be separated. Polyethylene glycol coated silica gel as support has, however, been superseded by chemically bonded stationary phases. 

Silver nanoparticles of 23 nm size were formed in aqueous medium by chemical reduction of silver nitrate in excess of aqueous sodium borohydride. To examine the aggregation of the produced silver nanoparticles they were coated either with polyethylene glycol or poly(diallyldimethylammonium chloride). 

Antithrombonic esters, including co-poly-(A,A -sebacoyl-bis-(L-leucine)-l,6-hexylene diester), (III), and polyethylene glycol derivatives, (IV), were prepared by Pacetti [3] and Hossainy [4], respectively, and used as bio-absorbable stent coatings. 

Multiple inking is possible using microfluidic networks over the PDMS stamps.Papra, A. Bernard, A. Juncker, D. Larsen, N. B. Michel, B. Delamarche, E. Microfluidic Networks Made of Poly(Dimethylsiloxane), Si, and Au Coated With Polyethylene Glycol for Patterning Proteins Onto Surfaces. Langmuir 2001, 17, 4090-4095... 

FIGURE 27-17 Typical chromatograms from open tubular columns coated with (a) polydimethyl siloxane (b) 5% (phenyl methyldimethyl) siloxane (c) 50% (phenyl methyidimethyl) siloxane (d) 50% poly(trifluoropropyl-dimethyl) siloxane (e) polyethylene glycol (f) 50% poly(cyanopropyl-dimethyl) siloxane. (Courtesy of J W Scientific.)... 

Coating of silver nanoparticles with polyelectrolytes influences their stability against aggregation. Herein the silver nanoparticles were coated with positive weak poly(allylamine hydrochloride) (PAH, 70kDa or 15kDa) or neutral polyethylene glycol (PEG, 8 kDa) polyelectrolytes. 

On the other hand, biomedical applications are very limited in both in vivo and in vitro conditions due to the high toxicity of these nanoparticles to the cells (You-yu et al., 2014). Therefore, nanoparticles are coated with compounds, such as natural polymers (proteins and carbohydrates) (Nair et al., 2010), synthetic organic polymers (polyethylene glycol), polyvinyl alcohol, poly-L-lactic acid. 

Papra A, Bernard A, Juncker D, Larsen NB, Michel B, Delamarche E (2001) Microfluidic networks made of poly(dimethylsiloxane), Si, and Au coated with polyethylene glycol for patterning proteins onto surfaces. Langmuir 17 4090-4095... 

The equivalent chain-lengths (ECL) of the methyl ester derivatives of 79 unsaturated fatty acids have been determined by GC with fused silica columns coated with Carbowax 20M (polyethylene glycol), Silar 5CP, CP-Sil 84 (Chrompak/Vaiian) and a 5% phenyl-methyl silicone (Christie, 1988). CP-Sil 84 is equivalent to AT-SILAR-90, DB-23, Rtx-2330, SP-2330 [poly(80% biscyanopropyl)-20% cyanoptroylphenyl siloxane] (Grace, 2011). 

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