Polyactic acid

Silk fibers or monolayers of silk proteins have a number of potential biomedical applications. Biocompatibility tests have been carried out with scaffolds of fibers or solubilized silk proteins from the silkworm Bombyx mori (for review see Ref. [38]). Some biocompatibility problems have been reported, but this was probably due to contamination with residual sericin. More recent studies with well-defined silkworm silk fibers and films suggest that the core fibroin fibers show in vivo and in vivo biocompatibility that is comparable to other biomaterials, such as polyactic acid and collagen. Altmann et al. [39] showed that a silk-fiber matrix obtained from properly processed natural silkworm fibers is a suitable material for the attachment, expansion and differentiation of adult human progenitor bone marrow stromal cells. Also, the direct inflammatory potential of silkworm silk was studied using an in vitro system [40]. The authors claimed that their silk fibers were mostly immunologically inert in short and long term culture with murine macrophage cells. 

Abbreviations. IM, intramuscular PLA, polyactic acid SQ, subcutaneous PLGA, poly(lactide-co-glycolide). 

PLA (polyactic acid) Makes U.S. Debut in Thermoforming (Food) Packaging, PT, May 2003. 

TBC is used as a plasticizer that does not support fungal growth in cellulosic and vinyl resins (especially PVC), polyactic acid resins (as a biodegradable component), and furniture coatings. Also used as a solvent for nitrocellulose and lacquers intended for food contact applications. Additional applications include a defoaming agent in proteinaceous solutions. 

Alexander, H., Parsons, J. R., and Strauchler, I. D. (1981), Canine patellar tendon replacement with a polyactic acid polymer-filamentous carbon tissue scaffold, Orthop. Rev. 10 41-51. 

Dow (2010) PARALOID" BPM-515 Acrylic Impact Modifier for Polyactic Acid Resin, http //www.dow.com/assets/ attachments/business/plastics additives/ paraloid bpm/paraloid bpm-... 

Polyactic acid (PLA) Renewable and non-renewable High strength... 

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