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Poly Lactide-co-Glycolide

PD Scholes, AGA Coombes, L Ilium, SS Davis, M Yert, MC Davies. The preparation of sub-200 nm poly (lactide-co-glycolide) microspheres for site-specific drug delivery. J Control Rel 25 145-153, 1993. [Pg.288]

These representative aliphatic polyesters are often used in copolymerized form in various combinations, for example, poly(lactide-co-glycolide) (PLGA) [66-68] and poly(lactide-co-caprolactone) [69-73], to improve degradation rates, mechanical properties, processability, and solubility by reducing crystallinity. Other monomers such as 1,4-dioxepan-5-one (DXO) [74—76], 1,4-dioxane-2-one [77], and trimethylene carbonate (TMC) [28] (Fig. 2) have also been used as comonomers to improve the hydrophobicity of the aliphatic polyesters as well as their degradability and mechanical properties. [Pg.72]

Poly(lactide-co-glycolide) (PLGA), 13 741 Polylactide nanocomposites, improved, 20 308... [Pg.733]

AI700/poly-lactide-co-glycolide -1- PEG fluorocarbon Clinical trials [35]... [Pg.88]

Mallery SR, Shenderova A, Pei P, Begum S, Giminieri JR, Wilson RF, Gasto BG, Schuller DE, Morse MA, Effects of 10-hydroxycamptothecin, delivered from locally injectable poly(lactide-co-glycolide) microspheres, in a murine human oral squamous cell carcinoma regression model, Anticancer Res 21 1713-1722, 2001. [Pg.498]

Recent Developments in Metal-Catalyzed Ring-Opening Polymerization of Lactides and Glycolides Preparation of Poly lactides, Polyglycolide, and Poly(lactide-co-glycolide)... [Pg.219]

Keywords Metal catalysts Poly(glycolide) Poly(lactide) Poly(lactide-co-glycolide) Ring-opening polymerization Stereocontrol... [Pg.220]

Jung, T., A. Breitenbach, and T. Kissel, Sulfobutylated poly(vinyl alcohol)-graft-poly (lactide-co-glycolide)s facilitate the preparation of small negatively charged biodegradable nanospheres. J Control Release, 2000. 67(2-3) 157-69. [Pg.378]

Abbreviations. IM, intramuscular PLA, polyactic acid SQ, subcutaneous PLGA, poly(lactide-co-glycolide). [Pg.279]

Abbreviations. MPL, monophosphoryl lipid A PLG, poly(lactide-co-glycolide) CpG ODN, CpG oligo-deoxynucleotide. [Pg.338]

Polyesters, specifically polylactides and poly(lactide-co-glycolide)s have played a critical role in the development of polymer-based CR technologies. The biocompatibility and the well-established safety profiles of PLA and PLGA polymers have made them the polymer of choice for CR applications. However the off-patent status of these polymers makes them freely available for research in industry as well as academia. This has led to a vast number of patents covering various applications of these polymers within the drug delivery sector. Due to these issues, very limited scope remains to utilize these polymers to reformulate generic, off-patent drugs. [Pg.347]

L-PLA, Poly(L-lactide) Hy Hycosinebutylbromid PLGA, Poly(lactide-co-glycolide) (d) Thy, Thymopentine (e) HYAFF, Hyaluronic acid ethyl ether HC, Hidrocortisone (E) DMSO, Dimethylsulfoxide. [Pg.621]

Fig. 48 Formation of poly(lactide-co-glycolide) by copolymerization of lactide and glycol-ide... Fig. 48 Formation of poly(lactide-co-glycolide) by copolymerization of lactide and glycol-ide...
Abbreviations PBMA, poly (ethylene-co-butyl methacrylate) PC, phosphoryl choline PEVAc, poly (ethylene-co-vinyl autate) PLGA, poly (lactide-co-glycolide) SIBS, styrene-isobutylene-styrene SS,. ... [Pg.294]

See other pages where Poly Lactide-co-Glycolide is mentioned: [Pg.787]    [Pg.436]    [Pg.223]    [Pg.31]    [Pg.33]    [Pg.36]    [Pg.68]    [Pg.144]    [Pg.161]    [Pg.733]    [Pg.2]    [Pg.5]    [Pg.6]    [Pg.157]    [Pg.420]    [Pg.594]    [Pg.242]    [Pg.219]    [Pg.220]    [Pg.221]    [Pg.272]    [Pg.113]    [Pg.282]    [Pg.338]    [Pg.617]    [Pg.620]    [Pg.787]    [Pg.133]    [Pg.317]    [Pg.331]    [Pg.293]   
See also in sourсe #XX -- [ Pg.429 ]



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Co-poly

Glycolide

Lactid

Lactides

Poly glycolide

Poly lactide

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