Poisons toxicity

HCN is a systemic poison toxicity is due to inhibition of cytochrome oxidase, which prevents cellular utilization of oxygen. Inhibition of the terminal step of electron transport in cells of the brain results in loss of consciousness, respiratory arrest, and ultimately, death. Stimulation of the chemoreceptors of the carotid and aortic bodies produces a brief period of hyperpnea cardiac irregularities may also occur. The biochemical mechanisms of cyanide action are the same for all mammalian species. HCN is metabolized by the enzyme rhodanese which catalyzes the transfer of sulfur from thiosulfate to cyanide to yield the relatively nontoxic thiocyanate. 

Symptoms of exposure Contact with skin may cause sensitization dermatitis. Ingestion may cause severe poisoning. Toxic symptoms include headache, nausea, vomiting, abdominal pain, and yellow coloration of skin (Patnaik, 1992). 

An acute poison toxic symptoms are similar to other soluble salts of barium (see Barium). 

Poisonous (toxic) substances. These are likely to either cause death, serious injury, or harm to human health if they are swallowed, inhaled, or come in contact with the skin. 

Gas, Noxious. Any poisonous (toxic) gas or a gas with strong unpleasant odor Ref Hackh s Diet (1944), 368-R... 

Epichlorohydrin (l-chloro-2,3-epoxypropane). Widely available. Used to epoxy activate the Sepharose CL-6B beads or other surfaces. The extent of epoxy activation of beads may be determined see Note 2). A high-purity (+99%) or equivalent should be used. It is a very unstable compound and must be stored at 0-4°C in an anhydrous environment. Hazards Flammable, poison, toxic by inhalation or contact with skin, and if swallowed may cause cancer. Toxicity data LD50 90 mg/kg oral, rat. Should be handled in a fume hood with safety glasses and gloves, and treated as a possible cancer hazard. 

Poisonous (toxic) and infectious substances 6.1 Poisonous (toxic) substances 6.2 Infectious substances Substances liable either to cause death or serious injury or to harm human health if swallowed or inhaled or by skin contact. Substances containing viable microorganisms or their toxins which are known, or suspected, to cause disease in animals or humans. 

Sulfluramid is the only member of sulfonamide class. It is a contact and stomach poison toxicant used in ant, termite, and cockroach baits. Its oral LD50 in rats is 2500 mg/kg. 

SAFETY PROFILE A poison. Toxic by inhalation. A flammable liquid. When heated to decomposition it emits ver toxic fumes of SOx. See also MERCAPTANS. 

Standard cardiorespiratory resuscitation and antiarrhythmia treatment are used for acute solvent poisoning. Toxicity from carbon tetrachloride and chloroform involves the generation of phosgene (a 1914-18 war gas) which is inactivated by cysteine, and by glutathione which is formed from cysteine treatment with N-acetylcysteine, as for poisoning with paracetamol, is therefore recommended. 

Staphylococcus aureus Gram-positive, aerobic, catalase-positive cocci Skin contaminant Food poisoning Toxic shock syndrome Fyogenic infections... 

Use Military poison (toxic suffocant) making crys-tal-violet-type coloring agents. 

Hazard A poison. Toxic by skin absorption. TLV 10 ppm. Highly flammable, dangerous fire and explosion risk, can be ignited by friction. Explosive limits in air 1-50%. 

Hazard A poison. Toxic by inhalation, strong irritant to tissue. 

Hazard Suspected carcinogen and poisonous. Toxic by ingestion. 

Type of poison Toxic dose Period of the effect... 

Poisonous (toxic) and infectious substances 6.1 Poisonous (toxic) substances, e.g. potassium cyanide. 

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